Human Disease and Mouse Model Detail

Human Disease

Focal Segmental Glomerulosclerosis 2; FSGS2
OMIM ID: 603965

Synonyms

Glomerulosclerosis, Focal Segmental, 2

View all models

View ALL (3) mouse models for this human disease.

Genes and
mouse models

Mutations in human and/or mouse homologs are associated with this disease

*Gene is associated with the disease in this species
Mouse Homologs	Human Homologs	Mouse Models	Mouse : Human Homology Class
Trpc6	TRPC6*		1:1 Homology

Transgenes and
other genome features

Transgenes and other genome features developed in mice to model this disease.

	Transgenes and Other Genome Features	Mouse Models
	Tg(NPHS2-Trpc6)F419Walz	View 1 model
	Tg(NPHS2-Trpc6*E896K)F75aWalz	View 1 model
	Tg(NPHS2-Trpc6*P111Q)F615Walz	View 1 model

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(NPHS2-Trpc6)F419Walz/0	involves: C57BL/6J * CBA/J	J:165112	View

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(NPHS2-Trpc6*E896K)F75aWalz/0	involves: C57BL/6J * CBA/J	J:165112	View

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(NPHS2-Trpc6*P111Q)F615Walz/0	involves: C57BL/6J * CBA/J	J:165112	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 06/05/2013 MGI 5.13