| Human Disease |
Frontotemporal Dementia; FTD OMIM ID: 600274 |
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| Synonyms | Dementia, Frontotemporal, with Parkinsonism; Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex; DDPAC; Frontotemporal Dementia with Parkinsonism; Frontotemporal Dementia-Amyotrophic Lateral Sclerosis; FTD-ALS; Frontotemporal Lobar Degeneration with Tau Inclusions; Frontotemporal Lobe Dementia; FLDEM; FTDP17; Ftld with Tau Inclusions; Multiple System Tauopathy with Presenile Dementia; MSTD; Wilhelmsen-Lynch Disease; WLD | ||||||||||||||||||||||||||||||
| View all models | View ALL (10) mouse models for this human disease. | ||||||||||||||||||||||||||||||
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Genes and mouse models |
Mutations in human and/or mouse homologs are associated with this disease
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Transgenes and other genome features |
Transgenes and other genome features developed in mice to model this disease.
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| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Camk2a-MAPT*R406W)748Atak/0 |
involves: C57BL/6 * SJL | J:100958 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Prnp-MAPT)43Vle/0 |
involves: C57BL/6 * DBA/2 | J:61052 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Prnp-MAPT*P301L)JNPL3Hlmc/? |
involves: C57BL/6 * DBA/2 | J:63887 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Prnp-TARDBP*A315T)95Balo/0 |
involves: C57BL/6 * CBA | J:153197 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Thy1-MAPT*K369I)K3Gotz/0 |
B6.Cg-Tg(Thy1-MAPT*K369I)K3Gotz | J:143439 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Thy1-MAPT*V337M)1Godt/0 |
involves: C57BL/6J * CBA/Ca | J:143018 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Thy1-TARDBP)4Singh/Tg(Thy1-TARDBP)4Singh |
involves: C57BL/6J * SJL/J | J:157550 | View |
| Tg(Thy1-TARDBP)4Singh/0 |
involves: C57BL/6J * SJL/J | J:157550 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Thy1-TARDBP)6Singh/Tg(Thy1-TARDBP)6Singh |
involves: C57BL/6 * C57BL/6J * SJL | J:157550 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Tuba1-MAPT)14Vle/0 |
involves: C57BL/6 * SJL | J:78400 | View |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/22/2013 MGI 5.13 |
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