| Human Disease |
Parkinson Disease 2, Autosomal Recessive Juvenile; PARK2 OMIM ID: 600116 |
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| Synonyms | Parkinson Disease, Juvenile, Autosomal Recessive; PDJ; Parkinsonism, Early-Onset, with Diurnal Fluctuation; EPDF | |||||||||||||||||||||
| View all models | View ALL (10) mouse models for this human disease. | |||||||||||||||||||||
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Genes and mouse models |
Mutations in human and/or mouse homologs are associated with this disease
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Transgenes and other genome features |
Transgenes and other genome features developed in mice to model this disease.
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| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Park2tm1Roo/Park2tm1Roo |
either: 129S2/SvPas or (involves: 129S2/SvPas * C57BL/6) | J:85561 | View |
| Park2tm1Shn/Park2tm1Shn |
involves: 129S4/SvJae | J:86377 | View |
| Park2tm1Tmd/Park2tm1Tmd |
involves: C57BL/6 | J:91487 | View |
| Park2tm1Roo/Park2tm1Roo |
involves: 129S2/SvPas | J:125148 | View |
| Park2tm1Ykt/Park2tm1Ykt Tg(PDGFB-GPR37)20Ryot/0 |
involves: 129P2/OlaHsd * C57BL/6 | J:140326 | View |
| Park2tm1Ykt/Park2tm1Ykt Tg(Prp-GPR37)1Ryot/0 |
involves: 129P2/OlaHsd * C3H * C57BL/6 | J:140326 | View |
| Park2tm1Ccs/Park2tm1Ccs |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:168847 | View |
| Park2tm1Ykt/Park2tm1Ykt Tg(PDGFB-GPR37)20Ryot/Tg(PDGFB-GPR37)20Ryot |
involves: 129P2/OlaHsd * C57BL/6 | J:140326 | View |
| Park2tm1Ykt/Park2tm1Ykt Tg(Prp-GPR37)1Ryot/Tg(Prp-GPR37)1Ryot |
involves: 129P2/OlaHsd * C3H * C57BL/6 | J:140326 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Slc6a3-PARK2*Q311X)AXwy/0 |
FVB/NJ-Tg(Slc6a3-PARK2*Q311X)AXwy | J:146833 | View |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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