Human Disease and Mouse Model Detail

Human Disease

Androgen Insensitivity Syndrome; AIS
OMIM ID: 300068

Synonyms

Androgen Receptor Deficiency; AR Deficiency; DHTR Deficiency; Dihydrotestosterone Receptor Deficiency; Testicular Feminization Syndrome; TFM

View all models

View ALL (10) mouse models for this human disease.

Genes and
mouse models

Mutations in human and/or mouse homologs are associated with this disease

*Gene is associated with the disease in this species
Mouse Homologs	Human Homologs	Mouse Models	Mouse : Human Homology Class
Ar*	AR*	View 8 models	1:1 Homology
Fkbp4*	FKBP4	View 2 models	1:1 Homology

Mouse Models

Human Disease Modeled: Androgen Insensitivity Syndrome; AIS
Associated Mouse Gene: Ar

Allelic Composition	Genetic Background	Reference	Phenotypes
Artm1.1Verh/Y	involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6	J:88169	View
Artm1.1Jdz/Y	B6.129X1-Artm1.1Jdz	J:123057	View
ArTfm/Y Tg(TSPY)9Jshm/0	involves: NMRI * STOCK EdaTa Atp7aMo-blo	J:140803	View
Artm1.1Jdz/Y	involves: 129X1/SvJ * C57BL/6	J:122327	View
Artm1Ska/Y Tg(CMV-cre)1Ipc/?	involves: C57BL/6 * CBA	J:85484	View
ArTfm/Y	involves: NMRI * STOCK EdaTa Atp7aMo-blo	J:140803	View
ArTfm/Y	involves: STOCK EdaTa Atp7aMo-blo	J:140803	View
ArTfm/Y	STOCK EdaTa Atp7aMo-blo/+ +	J:5173	View

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
Artm4(AR)Dmr/Y	involves: 129S1/Sv * C57BL/6J	J:104360	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 05/22/2013 MGI 5.13