Human Disease and Mouse Model Detail

Human Disease

Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
OMIM ID: 236600

Synonyms

Hydrocephaly; Ventriculomegaly

View all models

View ALL (16) mouse models for this human disease.

Genes and
mouse models

Mutations in human and/or mouse homologs are associated with this disease

*Gene is associated with the disease in this species
Mouse Homologs	Human Homologs	Mouse Models	Mouse : Human Homology Class
4930444A02Rik*	SGK196	View 1 model	1:1 Homology
Add1*	ADD1	View 1 model	1:1 Homology
Ak7*	AK7	View 1 model	1:1 Homology
Ak8*	AK8	View 1 model	1:1 Homology
Celsr2*	CELSR2	View 1 model	1:1 Homology
Dpcd*	DPCD	View 1 model	1:1 Homology
E2f5*	E2F5	View 1 model	1:1 Homology
Fzd3*	FZD3	View 1 model	1:1 Homology
hhy*		View 1 model
Hydin*		View 1 model	1:0 Homology
Kif27*	KIF27	View 1 model	1:1 Homology
Mboat7*	MBOAT7	View 1 model	1:1 Homology
Nme5*	NME5	View 1 model	1:1 Homology
Nme7*	NME7	View 1 model	1:1 Homology
Stk36*	STK36	View 1 model	1:1 Homology
Ulk4*	ULK4	View 1 model	1:1 Homology

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: 4930444A02Rik

Allelic Composition	Genetic Background	Reference	Phenotypes
4930444A02RikGt(OST243203)Lex/4930444A02RikGt(OST243203)Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: Add1

Allelic Composition	Genetic Background	Reference	Phenotypes
Add1tm1Llp/Add1tm1Llp	involves: 129P2/OlaHsd * 129S1/SvImJ * C57BL/6J	J:138919	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: Ak7

Allelic Composition	Genetic Background	Reference	Phenotypes
Ak7Gt(OST434404)Lex/Ak7Gt(OST434404)Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: Ak8

Allelic Composition	Genetic Background	Reference	Phenotypes
Ak8Gt(OST16378)Lex/Ak8Gt(OST16378)Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: Celsr2

Allelic Composition	Genetic Background	Reference	Phenotypes
Celsr2tm1Lex/Celsr2tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: Dpcd

Allelic Composition	Genetic Background	Reference	Phenotypes
Dpcd/PollGt(OST280355)Lex/Dpcd/PollGt(OST280355)Lex	involves: 129S5/SvEvBrd * C57BL/6Brd-Tyrc-Brd	J:185566	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: E2f5

Allelic Composition	Genetic Background	Reference	Phenotypes
E2f5tm1Dli/E2f5tm1Dli	either: (involves: 129S1/Sv * BALB/c) or (involves: 129S1/Sv * C57BL/6)	J:47283	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: Fzd3

Allelic Composition	Genetic Background	Reference	Phenotypes
Fzd3tm1(FZD3)Lex/Fzd3tm1(FZD3)Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: hhy

Allelic Composition	Genetic Background	Reference	Phenotypes
hhy/hhy	involves: BALB/cHeA * STS/A	J:93608	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: Hydin

Allelic Composition	Genetic Background	Reference	Phenotypes
Hydinhy3/Hydinhy3	involves: CBA	J:5426	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: Kif27

Allelic Composition	Genetic Background	Reference	Phenotypes
Kif27Gt(OST441915)Lex/Kif27Gt(OST441915)Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: Mboat7

Allelic Composition	Genetic Background	Reference	Phenotypes
Mboat7tm1Lex/Mboat7tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: Nme5

Allelic Composition	Genetic Background	Reference	Phenotypes
Nme5tm1Lex/Nme5tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: Nme7

Allelic Composition	Genetic Background	Reference	Phenotypes
Nme7Gt(OST31116)Lex/Nme7Gt(OST31116)Lex	involves: 129S5/SvEvBrd * C57BL/6Brd-Tyrc-Brd	J:185566	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: Stk36

Allelic Composition	Genetic Background	Reference	Phenotypes
Stk36tm1Lex/Stk36tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: Hydrocephalus, Nonsyndromic, Autosomal Recessive 1; HYC1
Associated Mouse Gene: Ulk4

Allelic Composition	Genetic Background	Reference	Phenotypes
Ulk4tm1Lex/Ulk4tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

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