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Human Disease and Mouse Model Detail
Human Disease Diabetes Mellitus, Insulin-Dependent; IDDM
OMIM ID: 222100
Synonyms Diabetes Mellitus, Insulin-Dependent; Diabetes Mellitus, Type I
View all models View ALL (78) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Gene is associated with the disease in this species
      Mouse Homologs Human Homologs Mouse Models Mouse : Human
Homology Class
     Cd38* CD38 View 1 model 1:1 Homology
Cdk4* CDK4 View 1 model 1:1 Homology
E2f1* E2F1 View 1 model 1:1 Homology
Fas* FAS View 2 models 1:1 Homology
Foxo1* FOXO1 View 1 model 1:1 Homology
Gad2* GAD2 View 1 model 1:1 Homology
Ifng* IFNG View 2 models 1:1 Homology
Ifngr2* IFNGR2 View 1 model 1:1 Homology
Ighm* View 3 models
Il1r1* IL1R1 View 1 model 1:1 Homology
Il4* IL4 View 2 models 1:1 Homology
Ins2* INS View 4 models 1:1 Homology
Pdpk1* PDPK1 View 1 model 1:1 Homology
Pdx1* PDX1 View 1 model 1:1 Homology
Prf1* PRF1 View 2 models 1:1 Homology
Ptprn2* PTPRN2 View 1 model 1:1 Homology
Sell* SELL View 4 models 1:1 Homology
Stat4* STAT4 View 4 models 1:1 Homology
Tnfsf4* TNFSF4 View 1 model 1:1 Homology
     Foxp3 FOXP3*   1:1 Homology
Hnf1a HNF1A*   1:1 Homology
Itpr3 ITPR3*   1:1 Homology
Oas1a, Oas1g OAS1*   2:1 Homology
Ptpn22 PTPN22*   1:1 Homology
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(H2-Ea-G6pc2)69Tkay View 1 model
  Tg(H2-Ea-Ins2)1Wehi View 1 model
  Tg(H2-Ead)12Lt View 1 model
  Tg(HLA-A/H2-D/B2M)1Dvs View 2 models
  Tg(Igh-6/Igh-V281)3Jwt View 2 models
  Tg(IghelMD4)4Ccg View 1 model
  Tg(Ins1-Cat,Tyr)25Pne View 2 models
  Tg(Ins2*Y16A)3Ell View 1 model
  Tg(Ins2-CALM1)26Ove View 2 models
  Tg(Ins2-CD80)3B7Flv View 4 models
  Tg(Ins2-CD86)12B70Flv View 1 model
  Tg(Ins2-Fasl)24Ach View 3 models
  Tg(Ins2-GP)34-20Olds View 2 models
  Tg(Ins2-HA)165Bri View 1 model
  Tg(Ins2-HBEGF)5Rin View 1 model
  Tg(Ins2-Nos2)31Okam View 1 model
  Tg(Ins2-Nos2)40Okam View 4 models
  Tg(Ins2-NP)25-3Olds View 2 models
  Tg(INS-MT2A,Tyr)1Pne View 2 models
  Tg(INS-SOD2)3Pne View 1 model
  Tg(Tcra/Tcrb)1Vbo View 1 model
  Tg(TcraAI4)1Dvs View 5 models
  Tg(TcraTcrbNY8.3)1Pesa View 1 model
References Disease References using Mouse Models (66)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory