Human Disease and Mouse Model Detail

Human Disease

Polycystic Kidney Disease 1; PKD1
OMIM ID: 173900

View all models

View ALL (31) mouse models for this human disease.

Genes and
mouse models

Mutations in human and/or mouse homologs are associated with this disease

*Gene is associated with the disease in this species
Mouse Homologs	Human Homologs	Mouse Models	Mouse : Human Homology Class
Pkd1*	PKD1*	View 19 models	1:1 Homology
b2b1146Clo*		View 1 model
b2b1163Clo*		View 1 model
b2b1200.1Clo*		View 1 model
b2b1200.2Clo*		View 1 model
b2b1200Clo*		View 1 model
b2b1291.2Clo*		View 1 model
b2b1291Clo*		View 1 model
Bicc1*	BICC1	View 1 model	1:1 Homology
Cep290*	CEP290	View 1 model	1:1 Homology
Pdk1*	PDK1	View 1 model	1:1 Homology
Tmem67*	TMEM67	View 2 models	1:1 Homology

Mouse Models

Human Disease Modeled: Polycystic Kidney Disease 1; PKD1
Associated Mouse Gene: Pkd1

Allelic Composition	Genetic Background	Reference	Phenotypes
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha	involves: 129S1/Sv * C57BL/6	J:193544	View
Pkd1tm1Djmp/Pkd1tm1Djmp	involves: 129P2/OlaHsd * C57BL/6	J:94582	View
Pkd1tm1Jzh/Pkd1tm1Jzh	either: (involves: 129S4/SvJae * C57BL/6) or (involves: 129S4/SvJae * BALB/c)	J:43193, J:72627, J:81443	View
Pkd1tm2.1Ggg/Pkd1tm2.1Ggg	involves: 129S4/SvJae * Black Swiss * C57BL/6	J:103719	View
Pkd1tm2Jzh/Pkd1tm2Jzh	either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)	J:72627	View
Pkd1tm3.1Jzh/Pkd1tm3.1Jzh	involves: 129P2/OlaHsd * C57BL/6	J:140012	View
Pkd1tm2Ggg/Pkd1tm2Ggg Tg(Nes-cre)Wme/0	involves: 129S4/SvJae * C57BL/6 * CBA	J:185855	View
Pkd1tm1.1Fqi/Pkd1tm1.1Fqi	involves: 129S6/SvEvTac	J:193175	View
Pkd1tm1Rsa/Pkd1⁺	involves: 129S4/SvJaeSor	J:72238	View
Pkd1tm1Jzh/Pkd1⁺	either: (involves: 129S4/SvJae * C57BL/6) or (involves: 129S4/SvJae * BALB/c)	J:43193, J:52573, J:72627	View
Pkd1tm1Bdgz/Pkd1⁺	involves: 129S1/Sv * 129X1/SvJ	J:130086	View
Pkd1tm2Jzh/Pkd1tm2Jzh	involves: 129S4/SvJae * C57BL/6	J:140012	View
Gpsm1tm1.1Lajb/Gpsm1tm1.1Lajb Pkd1tm1.1Fqi/Pkd1tm1.1Fqi	involves: 129S6/SvEvTac	J:193175	View
Pkd1tm1Ggg/Pkd1tm1Ggg	Not Specified	J:76062	View
Pkd1tm2Jzh/Pkd1⁺	either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)	J:72627	View
Pkd1tm3Jzh/Pkd1tm3Jzh Tg(Ggt1-cre)M3Egn/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	J:140012	View
Pkd1tm1Gztn/Pkd1tm1Gztn Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor⁺	involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6	J:162080	View
Pkd1tm2Ggg/Pkd1tm2Ggg Tg(MMTV-cre)4Mam/0	involves: 129S4/SvJae * FVB	J:103719	View
Pkd1tm2Som/Pkd1tm2.1Som Tg(Cdh16-cre)91Igr/0	involves: C57BL/6 * ICR * SJL	J:135301	View

Mouse Models

Human Disease Modeled: Polycystic Kidney Disease 1; PKD1
Associated Mouse Gene: b2b1146Clo

Allelic Composition	Genetic Background	Reference	Phenotypes
b2b1146Clo/b2b1146Clo	C57BL/6J-b2b1146Clo	J:175213	View

Mouse Models

Human Disease Modeled: Polycystic Kidney Disease 1; PKD1
Associated Mouse Gene: b2b1163Clo

Allelic Composition	Genetic Background	Reference	Phenotypes
b2b1163Clo/b2b1163Clo	C57BL/6J-b2b1163Clo	J:175213	View

Mouse Models

Human Disease Modeled: Polycystic Kidney Disease 1; PKD1
Associated Mouse Gene: b2b1200.1Clo

Allelic Composition	Genetic Background	Reference	Phenotypes
b2b1200.1Clo/b2b1200.1Clo	C57BL/6J-b2b1200.1Clo	J:175213	View

Mouse Models

Human Disease Modeled: Polycystic Kidney Disease 1; PKD1
Associated Mouse Gene: b2b1200.2Clo

Allelic Composition	Genetic Background	Reference	Phenotypes
b2b1200.2Clo/b2b1200.2Clo	C57BL/6J-b2b1200.2Clo	J:175213	View

Mouse Models

Human Disease Modeled: Polycystic Kidney Disease 1; PKD1
Associated Mouse Gene: b2b1200Clo

Allelic Composition	Genetic Background	Reference	Phenotypes
b2b1200Clo/b2b1200Clo	C57BL/6J-b2b1200Clo	J:175213	View

Mouse Models

Human Disease Modeled: Polycystic Kidney Disease 1; PKD1
Associated Mouse Gene: b2b1291.2Clo

Allelic Composition	Genetic Background	Reference	Phenotypes
b2b1291.2Clo/b2b1291.2Clo	C57BL/6J-b2b1291.2Clo	J:175213	View

Mouse Models

Human Disease Modeled: Polycystic Kidney Disease 1; PKD1
Associated Mouse Gene: b2b1291Clo

Allelic Composition	Genetic Background	Reference	Phenotypes
b2b1291Clo/b2b1291Clo	C57BL/6J-b2b1291Clo	J:175213	View

Mouse Models

Human Disease Modeled: Polycystic Kidney Disease 1; PKD1
Associated Mouse Gene: Bicc1

Allelic Composition	Genetic Background	Reference	Phenotypes
Bicc1b2b222Clo/Bicc1b2b222Clo	C57BL/6J-Bicc1b2b222Clo	J:175213	View

Mouse Models

Human Disease Modeled: Polycystic Kidney Disease 1; PKD1
Associated Mouse Gene: Cep290

Allelic Composition	Genetic Background	Reference	Phenotypes
Cep290b2b1454Clo/Cep290b2b1454Clo	C57BL/6J-Cep290b2b1454Clo	J:175213	View

Mouse Models

Human Disease Modeled: Polycystic Kidney Disease 1; PKD1
Associated Mouse Gene: Pdk1

Allelic Composition	Genetic Background	Reference	Phenotypes
Pdk1b2b1585Clo/Pdk1b2b1585Clo	C57BL/6J-Pdk1b2b1585Clo	J:175213	View

Mouse Models

Human Disease Modeled: Polycystic Kidney Disease 1; PKD1
Associated Mouse Gene: Tmem67

Allelic Composition	Genetic Background	Reference	Phenotypes
Tmem67b2b1163.1Clo/Tmem67b2b1163.1Clo	C57BL/6J-Tmem67b2b1163.1Clo	J:175213	View
Tmem67b2b1291.1Clo/Tmem67b2b1291.1Clo	C57BL/6J-Tmem67b2b1291.1Clo	J:175213	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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