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Human Disease and Mouse Model Detail
Human Disease Parkinson Disease 1, Autosomal Dominant; PARK1
OMIM ID: 168601
Synonyms Parkinson Disease; Parkinson Disease 1, Autosomal Dominant Lewy Body
View all models View ALL (19) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Gene is associated with the disease in this species
      Mouse Homologs Human Homologs Mouse Models Mouse : Human
Homology Class
     Snca* SNCA* View 6 models 1:1 Homology
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(PDGFB-SNCA)4Ema View 1 model
  Tg(Prnp-SNCA*A53T)23Mkle View 1 model
  Tg(Prnp-SNCA*A53T)25Mkle View 1 model
  Tg(Prnp-SNCA*A53T)83Vle View 2 models
  Tg(SNCA)ARyot View 1 model
  Tg(SNCA*E46K)3Elan View 1 model
  Tg(Snca-SNCA)#Galt View 1 model
  Tg(Th-SNCA*)1702Yosh View 1 model
  Tg(Thy1-SNCA)61Ema View 1 model
  Tg(Thy1-SNCA*A30P)18Pjk View 1 model
References Disease References using Mouse Models (27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory