| Human Disease |
Medulloblastoma; MDB OMIM ID: 155255 |
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| View all models | View ALL (31) mouse models for this human disease. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Genes and mouse models |
Mutations in human and/or mouse homologs are associated with this disease
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Transgenes and other genome features |
Transgenes and other genome features developed in mice to model this disease.
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| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Brca2tm1Brn/Brca2tm1Brn Trp53tm1Tyj/Trp53+ Tg(Nes-cre)1Kln/0 |
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL | J:144617 | View |
| Brca2tm1Brn/Brca2tm1Brn Trp53tm1Tyj/Trp53tm1Tyj Tg(Nes-cre)1Kln/0 |
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL | J:144617 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Cdkn2ctm1Bbd/Cdkn2ctm1Bbd Ptch1tm1Mps/Ptch1+ |
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ | J:102702 | View |
| Cdkn2ctm1Bbd/Cdkn2c+ Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129S1/Sv * 129S2/SvPas * C57BL/6 | J:102702 | View |
| Cdkn2ctm1Bbd/Cdkn2ctm1Bbd Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129S1/Sv * 129S2/SvPas * C57BL/6 | J:102702 | View |
| Cdkn2ctm1Bbd/Cdkn2ctm1Bbd Trp53tm1Brn/Trp53tm1Tyj Tg(Nes-cre)1Kln/0 |
involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL | J:102702 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Ptch1tm1Mps/Ptch1+ Tg(Atoh1-GFP)1Jejo/? |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 | J:144811 | View |
| Ptch1tm1Zim/Ptch1+ |
involves: 129/Sv * CD-1 | J:79666 | View |
| Ptch1tm1Mps/Ptch1+ Ptch2tm1Pmc/Ptch2+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:112118 | View |
| Cdkn2ctm1Bbd/Cdkn2ctm1Bbd Ptch1tm1Mps/Ptch1+ |
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ | J:102702 | View |
| Ptch1tm1Mps/Ptch1+ Ptch2tm1Pmc/Ptch2tm1Pmc |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:112118 | View |
| Ptch1tm1Bjw/Ptch1tm1Bjw Tg(Atoh1-cre/Esr1*)14Fsh/0 |
involves: 129T2/SvEms * FVB/N | J:139573 | View |
| Ptch1tm1Mps/Ptch1+ |
involves: 129S1/Sv * 129X1/SvJ | J:144811 | View |
| Ptch1tm1Bjw/Ptch1tm1Bjw Tg(Atoh1-cre)1Bfri/0 |
involves: 129T2/SvEms * C57BL/6 * CBA | J:139573 | View |
| Ptch1tm1Mps/Ptch1+ Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129 * 129S2/SvPas * C57BL/6 | J:67452 | View |
| Ptch1tm1Bjw/Ptch1tm1Bjw Tg(GFAP-cre)25Mes/0 |
involves: 129T2/SvEms * FVB/N | J:139573 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brd/Trp53tm1Brd Tg(Gfap-cre)2Brn/0 |
involves: 129 * 129S7/SvEvBrd * FVB/N | J:61961 | View |
| Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brn/Trp53tm1Brn Tg(Gfap-cre)2Brn/0 |
involves: 129P2/OlaHsd * FVB/N | J:61961 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| SufuGt(XB699)Byg/Sufu+ Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 | J:173443 | View |
| Lig4tm1Icrf/Lig4tm1Icrf Trp53tm1Tyj/Trp53tm1Tyj |
either: (involves: 129P2/OlaHsd * 129S2/SvPas) or (involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ) | J:173443 | View |
| Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brd/Trp53tm1Brd Tg(Gfap-cre)2Brn/0 |
involves: 129 * 129S7/SvEvBrd * FVB/N | J:61961 | View |
| Cdkn2ctm1Bbd/Cdkn2c+ Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129S1/Sv * 129S2/SvPas * C57BL/6 | J:102702 | View |
| Cdkn2ctm1Bbd/Cdkn2ctm1Bbd Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129S1/Sv * 129S2/SvPas * C57BL/6 | J:102702 | View |
| Rag1tm1Mom/Rag1tm1Mom Trp53tm1Brd/Trp53tm1Brd Xrcc5tm1Dbr/Xrcc5tm1Dbr |
involves: 129S7/SvEvBrd * C57BL | J:141515 | View |
| Rb1tm2Brn/Rb1tm2Brn Trp53tm1Brn/Trp53tm1Brn Tg(Gfap-cre)2Brn/0 |
involves: 129P2/OlaHsd * FVB/N | J:61961 | View |
| Ptch1tm1Mps/Ptch1+ Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129 * 129S2/SvPas * C57BL/6 | J:67452 | View |
| Cdkn2ctm1Bbd/Cdkn2ctm1Bbd Trp53tm1Brn/Trp53tm1Tyj Tg(Nes-cre)1Kln/0 |
involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL | J:102702 | View |
| Brca2tm1Brn/Brca2tm1Brn Trp53tm1Tyj/Trp53+ Tg(Nes-cre)1Kln/0 |
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL | J:144617 | View |
| Brca2tm1Brn/Brca2tm1Brn Trp53tm1Tyj/Trp53tm1Tyj Tg(Nes-cre)1Kln/0 |
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL | J:144617 | View |
| Trp53tm1Brd/Trp53tm1Brd Xrcc4tm2.1Fwa/Xrcc4tm2Fwa Tg(Nes-cre)1Kln/0 |
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL | J:109585 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Trp53tm1Brd/Trp53tm1Brd Xrcc4tm2.1Fwa/Xrcc4tm2Fwa Tg(Nes-cre)1Kln/0 |
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL | J:109585 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Ptch1tm1Mps/Ptch1+ Ptch2tm1Pmc/Ptch2+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:112118 | View |
| Ptch1tm1Mps/Ptch1+ Ptch2tm1Pmc/Ptch2tm1Pmc |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:112118 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| SufuGt(XB699)Byg/Sufu+ Trp53tm1Tyj/Trp53tm1Tyj |
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 | J:173443 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Neurod2-Smo*A1)199Jols/Tg(Neurod2-Smo*A1)199Jols |
C57BL/6-Tg(Neurod2-Smo*A1)199Jols | J:189258 | View |
| Tg(Neurod2-Smo*A1)199Jols/0 |
C57BL/6-Tg(Neurod2-Smo*A1)199Jols | J:93861 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Neurod2-Smo*A2)#Jols/0 |
C57BL/6-Tg(Neurod2-Smo*A2)#Jols | J:189258 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(tetO-TAg,CMV-rtTA)123Yihu/0 |
involves: FVB/N | J:141623 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Tg(GFAP-cre)25Mes/0 |
involves: 129X1/SvJ * FVB/N | J:139574 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Olig2tm2(TVA,cre)Rth/Olig2+ |
involves: 129 * 129X1/SvJ | J:139574 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(GFAP-tTA)67Pop/0 Tg(tetO-Ifng)184Pop/0 |
involves: 129S/SvEv * C57BL/6 * DBA/2 | J:94092 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Tlx3tm1(cre)Qima/Tlx3+ |
involves: 129X1/SvJ | J:139574 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc Tg(Atoh1-cre/Esr1*)14Fsh/0 |
involves: 129X1/SvJ * FVB/N | J:139574 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(GFAP-tTA)67Pop/0 Tg(tetO-Ifng)184Pop/0 |
B6.Cg-Tg(GFAP-tTA)67Pop Tg(tetO-Ifng)184Pop | J:94092 | View |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 06/05/2013 MGI 5.13 |
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