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Human Disease and Mouse Model Detail
Human Disease Systemic Lupus Erythematosus; SLE
OMIM ID: 152700
Synonyms Systemic Lupus Erythematosus
View all models View ALL (54) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Human Homologs Mouse Homologs Mouse Models Homology Source
     DNASE1* Dnase1* View 1 model HomoloGene
FCGR2B* Fcgr2b* View 2 models HomoloGene
     C1QA C1qa* View 1 model HomoloGene and HGNC
C4A, C4B C4b*, C4a View 1 model HomoloGene and HGNC
CD40LG Cd40lg* View 1 model HomoloGene and HGNC
CDKN1A Cdkn1a* View 2 models HomoloGene
DEF6 Def6* View 1 model HomoloGene and HGNC
EP300 Ep300* View 1 model HomoloGene and HGNC
FAS Fas* View 5 models HomoloGene
GADD45A Gadd45a* View 2 models HomoloGene and HGNC
IFIH1 Ifih1* View 2 models HomoloGene and HGNC
IKZF3 Ikzf3* View 1 model HomoloGene and HGNC
JAK1 Jak1* View 1 model HomoloGene and HGNC
JUNB Junb* View 1 model HomoloGene and HGNC
LYN Lyn* View 2 models HomoloGene and HGNC
MAN2A1 Man2a1* View 1 model HomoloGene
MTA2 Mta2* View 1 model HomoloGene
POLB Polb* View 1 model HomoloGene and HGNC
PPARG Pparg* View 1 model HomoloGene
PRDM1 Prdm1* View 1 model HomoloGene
PTPRC Ptprc* View 3 models HomoloGene
RASGRP1 Rasgrp1* View 1 model HomoloGene
RASSF5 Rassf5* View 1 model HomoloGene and HGNC
RC3H1 Rc3h1* View 1 model HomoloGene and HGNC
RXRA Rxra* View 1 model HomoloGene and HGNC
TLR7 Tlr7* View 1 model HomoloGene
TNFRSF13B Tnfrsf13b* View 1 model HomoloGene and HGNC
TRAF3IP2 Traf3ip2* View 2 models HomoloGene and HGNC
TROVE2 Trove2* View 3 models HomoloGene and HGNC
     BANK1* Bank1   HomoloGene
CTLA4* Ctla4   HomoloGene and HGNC
PTPN22* Ptpn22 View 1 model HomoloGene
TREX1* Trex1   HomoloGene and HGNC
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Igh-J View 4 models
  Tg(ACTB-TNFRSF6B)754Jwu View 1 model
  Tg(Igh-V-CD40lg)#Tsub View 1 model
  Tg(Tlr7)1Boll View 1 model
  Yaa View 5 models
References Disease References using Mouse Models (56)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory