Human Disease and Mouse Model Detail

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Human Disease

Cerebral Arteriopathy, Autosomal Dominant, with Subcortical Infarcts and Leukoencephalopathy; CADASIL
OMIM ID: 125310

Synonyms

CASIL; Dementia, Hereditary Multi-Infarct Type

View all models

View ALL (5) mouse models for this human disease.

Genes and
mouse models

Mutations in human and/or mouse homologs are associated with this disease

*Gene is associated with the disease in this species
Mouse Homologs	Human Homologs	Mouse Models	Mouse : Human Homology Class
Notch3*	NOTCH3*	View 4 models	1:1 Homology

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 05/08/2013 MGI 5.13

Allelic Composition	Genetic Background	Reference	Phenotypes
Notch3tm1.1Dwr/Notch3tm1.1Dwr	involves: 129S/SvEv * Swiss	J:191454	View
Notch3tm1.1Dwr/Notch3⁺	involves: 129S/SvEv * Swiss	J:191454	View
Gt(ROSA)26Sortm3(NOTCH3*R1031C)Sat/Gt(ROSA)26Sor⁺ Notch3Gt(PST033)Byg/Notch3Gt(PST033)Byg Tg(Tagln-cre)1Her/0	involves: 129 * C57BL/6 * SJL	J:171887	View
Gt(ROSA)26Sortm2(NOTCH3*C455R)Sat/Gt(ROSA)26Sor⁺ Notch3Gt(PST033)Byg/Notch3Gt(PST033)Byg Tg(Tagln-cre)1Her/0	involves: 129 * C57BL/6 * SJL	J:171887	View

Allelic Composition	Genetic Background	Reference	Phenotypes
Gt(ROSA)26Sortm3(NOTCH3*R1031C)Sat/Gt(ROSA)26Sor⁺ Tg(Tagln-cre)1Her/0	involves: 129S2/SvEv * 129S6/SvEvTac * C57BL/6 * SJL	J:171887	View