| Human Disease |
Hepatocellular Carcinoma OMIM ID: 114550 |
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| Synonyms | Cancer, Hepatocellular; HCC; Liver Cancer; Liver Cell Carcinoma; LCC | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| View all models | View ALL (35) mouse models for this human disease. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Genes and mouse models |
Mutations in human and/or mouse homologs are associated with this disease
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Transgenes and other genome features |
Transgenes and other genome features developed in mice to model this disease.
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| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Apctm2.1Cip/Apctm2.1Cip |
involves: 129P2/OlaHsd * C57BL/6N | J:94721 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Abcb4tm1Bor/Abcb4tm1Bor |
either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * FVB/N) | J:21232 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Cdkn1atm1(HBsAg)Xya/Cdkn1atm1(HBsAg)Xya |
either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View |
| Cdkn1atm2(HBx)Xya/Cdkn1atm2(HBx)Xya |
either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View |
| Cdkn1atm2(HBx)Xya/Cdkn1a+ |
either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View |
| Cdkn1atm1(HBsAg)Xya/Cdkn1a+ |
either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Foxm1tm1Rhc/Foxm1tm1Rhc |
involves: 129X1/SvJ | J:89472 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Mcm9Gt(AW0655)Wtsi/Mcm9Gt(AW0655)Wtsi |
involves: 129P2/OlaHsd * C3HeB/FeJ | J:177420 | View |
| Mcm9Gt(XG743)Byg/Mcm9Gt(XG743)Byg |
involves: 129P2/OlaHsd * C3HeB/FeJ | J:177420 | View |
| Mcm9Gt(AW0655)Wtsi/Mcm9Gt(XG743)Byg |
involves: 129P2/OlaHsd * C3HeB/FeJ | J:177420 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Nfe2l1tm1Jefc/Nfe2l1tm1Ywk Tg(Alb-cre)21Mgn/0 |
involves: 129X1/SvJ * C57BL/6J | J:97188 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Nr1h4tm1Gonz/Nr1h4tm1Gonz |
involves: 129X1/SvJ * C57BL/6 | J:118204, J:170790 | View |
| Nr1h4tm1Gonz/Nr1h4tm1Gonz |
involves: 129X1/SvJ * C57BL/6N | J:121075, J:170790 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Ptentm2Mak/Ptentm2Mak Tg(Alb-cre)21Mgn/0 |
involves: 129P2/OlaHsd * C57BL/6 * DBA | J:138099 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Rb1tm3Tyj/Rb1tm3Tyj Rbl1tm1Tyj/Rbl1tm1Tyj Rbl2tm2.1Tyj/Rbl2tm2.1Tyj |
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 | J:177573 | View |
| Rb1tm3Tyj/Rb1tm3Tyj Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:172430 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Rb1tm3Tyj/Rb1tm3Tyj Rbl1tm1Tyj/Rbl1tm1Tyj Rbl2tm2.1Tyj/Rbl2tm2.1Tyj |
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 | J:177573 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Rb1tm3Tyj/Rb1tm3Tyj Rbl1tm1Tyj/Rbl1tm1Tyj Rbl2tm2.1Tyj/Rbl2tm2.1Tyj |
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 | J:177573 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| TxnipHyplip1/TxnipHyplip1 |
HcB19/Dem-TxnipHyplip1 | J:112292 | View |
| TxnipHyplip1/TxnipHyplip1 |
involves: CAST/Ei * HcB19/Dem | J:112292 | View |
| TxnipHyplip1/Txnip+ |
involves: CAST/Ei * HcB19/Dem | J:112292 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Uacatm1Kiy/Uacatm1Kiy |
B6.129P2-Uacatm1Kiy | J:157049 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Alb-E2F1)8Sst/0 |
involves: C57BL/6J * CBA/J | J:65354, J:101128, J:170790 | View |
| Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+ Tg(Alb-E2F1)8Sst/0 |
involves: C57BL/6 * CBA | J:101128, J:170790 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Alb-TAg)1Gjh/0 |
C3.Cg-Tg(Alb-TAg)1Gjh | J:105110 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Alb-TAg)#Arnd/0 |
C3Fe.Cg-Tg(Alb-TAg)#Arnd | J:171880 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(tetO-MET)23Rwng/0 Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:69731 | View |
| Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:93899, J:172430 | View |
| Rb1tm3Tyj/Rb1tm3Tyj Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:172430 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Myl2-FGF19)1Dfre/? |
involves: FVB | J:77160, J:187236 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Pklr-Myc)73Ak/0 |
B6.Cg-Tg(Pklr-Myc)73Ak | J:184496 | View |
| Tg(Pklr-Myc)73Ak/0 |
involves: C57BL/6 * DBA | J:185488 | View |
| Lect2tm1Ymg/Lect2tm1Ymg Tg(Pklr-Myc)73Ak/0 |
B6.Cg-Lect2tm1Ymg Tg(Pklr-Myc)73Ak | J:184496 | View |
| Tcra-Jtm1Tgi/Tcra-Jtm1Tgi Tg(Pklr-Myc)73Ak/0 |
B6.Cg-Tcra-Jtm1Tgi Tg(Pklr-Myc)73Ak | J:184496 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(SERPINC1-SV40)A1Pbr/Tg(SERPINC1-SV40)A1Pbr |
involves: C57BL/6 * DBA/2 | J:101541 | View |
| Tg(SERPINC1-SV40)A1Pbr/0 |
involves: C57BL/6 * DBA/2 | J:101541 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| X/Tg(SERPINC1-SV40)BPbr |
involves: C57BL/6 * DBA/2 | J:101541, J:84204 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:93899, J:172430 | View |
| Rb1tm3Tyj/Rb1tm3Tyj Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:172430 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+ Tg(MtTGFA)42Lmb/0 |
involves: C57BL/6 * CBA * CD-1 | J:34434 | View |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 06/05/2013 MGI 5.13 |
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