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Human Disease and Mouse Model Detail
Human Disease Hepatocellular Carcinoma
OMIM ID: 114550
Synonyms Cancer, Hepatocellular; HCC; Liver Cancer; Liver Cell Carcinoma; LCC
View all models View ALL (39) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Gene is associated with the disease in this species
      Mouse Homologs Human Homologs Mouse Models Mouse : Human
Homology Class
     Apc* APC* View 1 model 1:1 Homology
     Abcb4* ABCB4 View 1 model 1:1 Homology
Cdkn1a* CDKN1A View 4 models 1:1 Homology
Foxm1* FOXM1 View 1 model 1:1 Homology
Iqgap2* IQGAP2 View 1 model 1:1 Homology
Mcm9* MCM9 View 3 models 1:1 Homology
Nfe2l1* NFE2L1 View 1 model 1:1 Homology
Nr1h4* NR1H4 View 2 models 1:1 Homology
Pten* PTEN View 1 model 1:1 Homology
Rb1* RB1 View 2 models 1:1 Homology
Rbl1* RBL1 View 1 model 1:1 Homology
Rbl2* RBL2 View 1 model 1:1 Homology
Txnip* TXNIP View 3 models 1:1 Homology
Uaca* UACA View 1 model 1:1 Homology
     Axin1 AXIN1*   1:1 Homology
Casp8 CASP8*   1:1 Homology
CTNNB1*   0:1 Homology
Igf2r IGF2R*   1:1 Homology
Met MET*   1:1 Homology
Pdgfrl PDGFRL*   1:1 Homology
Pik3ca PIK3CA*   1:1 Homology
Trp53 TP53*   1:1 Homology
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(Alb-E2F1)8Sst View 2 models
  Tg(Alb-PDGFC)#Jcam View 1 model
  Tg(Alb-TAg)1Gjh View 1 model
  Tg(Alb-TAg)#Arnd View 1 model
  Tg(Cebpb-tTA)5Bjd View 3 models
  Tg(HBVX*,-Myc)#Skp View 1 model
  Tg(HBx)3Yu View 1 model
  Tg(Myl2-FGF19)1Dfre View 1 model
  Tg(Pklr-Myc)73Ak View 4 models
  Tg(SERPINC1-SV40)A1Pbr View 2 models
  Tg(SERPINC1-SV40)BPbr View 1 model
  Tg(tetO-MYC)36aBop View 2 models
References Disease References using Mouse Models (37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory