Excel File Text File *Disease is associated/modeled with this Gene or a homolog. More...
      Disease Term Human Homologs Mouse Homologs Mouse Models Homology Source
     low tension glaucoma OPTN* Optn* 1 model Alliance of Genome Resources
open-angle glaucoma MYOC* Myoc* 1 model Alliance of Genome Resources
     juvenile glaucoma PAX6 Pax6* 1 model Alliance of Genome Resources
low tension glaucoma SLC1A1 Slc1a1* 1 model Alliance of Genome Resources
low tension glaucoma SOD1 Sod1* 1 model Alliance of Genome Resources
low tension glaucoma SLC1A3 Slc1a3* 1 model Alliance of Genome Resources
primary open angle glaucoma GUCY1A1 Gucy1a1* 1 model Alliance of Genome Resources
     juvenile glaucoma MYOC* Myoc   Alliance of Genome Resources
low tension glaucoma TP53* Trp53   Alliance of Genome Resources
low tension glaucoma TNF* Tnf   Alliance of Genome Resources
low tension glaucoma MYOC* Myoc   Alliance of Genome Resources
low tension glaucoma CAV2* Cav2   Alliance of Genome Resources
low tension glaucoma APOE* Apoe   Alliance of Genome Resources
low tension glaucoma ADRB1* Adrb1   Alliance of Genome Resources
low tension glaucoma TLR4* Tlr4   Alliance of Genome Resources
open-angle glaucoma ADRB2* Adrb2   Alliance of Genome Resources
open-angle glaucoma AFAP1* Afap1   Alliance of Genome Resources
open-angle glaucoma APOE* Apoe   Alliance of Genome Resources
open-angle glaucoma CDKN2B* Cdkn2b   Alliance of Genome Resources
open-angle glaucoma GMDS* Gmds   Alliance of Genome Resources
open-angle glaucoma MEIS2* Meis2   Alliance of Genome Resources
open-angle glaucoma MTHFR* Mthfr   Alliance of Genome Resources
open-angle glaucoma OPTN* Optn   Alliance of Genome Resources
open-angle glaucoma PON1* Pon1   Alliance of Genome Resources
open-angle glaucoma TAP1* Tap1   Alliance of Genome Resources
open-angle glaucoma TNF* Tnf   Alliance of Genome Resources
primary open angle glaucoma MMP1* Mmp1a, Mmp1b   Alliance of Genome Resources
primary open angle glaucoma MYOC* Myoc   Alliance of Genome Resources
primary open angle glaucoma NOS3* Nos3   Alliance of Genome Resources
primary open angle glaucoma OGG1* Ogg1   Alliance of Genome Resources
primary open angle glaucoma OPTN* Optn   Alliance of Genome Resources
primary open angle glaucoma PON1* Pon1   Alliance of Genome Resources
primary open angle glaucoma SOD2* Sod2   Alliance of Genome Resources
primary open angle glaucoma THBS1* Thbs1   Alliance of Genome Resources
primary open angle glaucoma TLR4* Tlr4   Alliance of Genome Resources
primary open angle glaucoma TNF* Tnf   Alliance of Genome Resources
primary open angle glaucoma TP53* Trp53   Alliance of Genome Resources
primary open angle glaucoma WDR36* Wdr36   Alliance of Genome Resources
primary open angle glaucoma GSTT1* Gstt1   Alliance of Genome Resources
primary open angle glaucoma GSTM1*, GSTM5 Gstm1, Gstm2, Gstm3, Gstm6   Alliance of Genome Resources
primary open angle glaucoma ESR2* Esr2   Alliance of Genome Resources
primary open angle glaucoma CYP1B1* Cyp1b1   Alliance of Genome Resources
primary open angle glaucoma COL6A3* Col6a3   Alliance of Genome Resources
primary open angle glaucoma CDKN1A* Cdkn1a   Alliance of Genome Resources
primary open angle glaucoma CAV2* Cav2   Alliance of Genome Resources
primary open angle glaucoma ADIPOQ* Adipoq   Alliance of Genome Resources
primary open angle glaucoma ACVR1* Acvr1   Alliance of Genome Resources
primary open angle glaucoma CAV1* Cav1   Alliance of Genome Resources
primary open angle glaucoma APOE* Apoe   Alliance of Genome Resources
primary open angle glaucoma ADRB2* Adrb2   Alliance of Genome Resources
primary open angle glaucoma LAMB2* Lamb2   Alliance of Genome Resources
primary open angle glaucoma LOXL1* Loxl1   Alliance of Genome Resources

 
Transgenes and other genome features developed in mice to model this disease.
     Disease Term Transgenes and Other Genome Features Mouse Models
  low tension glaucoma Tg(TBK1)#Andm 2 models
  open-angle glaucoma Tg(Myoc*Y423H)#Sit 1 model
  open-angle glaucoma Tg(MYOC*Y437H)#Sit 1 model
  primary open angle glaucoma Tg(CMV-MYOC*Y437H)#Vcs 1 model
  primary open angle glaucoma Tg(OPTN*E50K,-EGFP)1Mde 1 model