tetralogy of Fallot Disease Ontology Browser

Disease Ontology Browser

tetralogy of Fallot (DOID:6419)
Alliance: disease page
Synonyms: Ventricular septal defect with pulmonary stenosis or atresia, dextraposition of aorta, and hypertrophy of right ventricle
Alt IDs: OMIM:187500, ICD10CM:Q21.3, ICD9CM:745.2, MESH:D013771, NCI:C84505, UMLS_CUI:C0039685

Term Browser
Genes (27)
Models (17)

Disease References using Mouse Models (15)

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Gja5

Allelic Composition	Genetic Background	Reference	Phenotypes
Gja5tm1Paul/Gja5tm1Paul	involves: 129S4/SvJae * C57BL/6	J:109301	View
Gja5tm1Paul/Gja5+	involves: 129S4/SvJae * C57BL/6	J:109301	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Nkx2-5

Allelic Composition	Genetic Background	Reference	Phenotypes
Nkx2-5tm2.1Mwc/Nkx2-5+	B6J.Cg-Nkx2-5^tm2.1Mwc/Mwc	J:239808	View
Nkx2-5tm3.1Mwc/Nkx2-5+	B6J.Cg-Nkx2-5^tm3.1Mwc/Mwc	J:239808	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Zfpm2

Allelic Composition	Genetic Background	Reference	Phenotypes
Zfpm2tm1Sho/Zfpm2tm1Sho	involves: 129S1/Sv	J:62879, J:78688	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Bmp10

Allelic Composition	Genetic Background	Reference	Phenotypes
Bmp10b2b2711Clo/Bmp10b2b2711Clo	C57BL/6J-Bmp10^b2b2711Clo	J:175213	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Cited2

Allelic Composition	Genetic Background	Reference	Phenotypes
Cited2tm1Ycy/Cited2tm1Ycy	involves: C57BL/6J	J:78364	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Dnah5

Allelic Composition	Genetic Background	Reference	Phenotypes
Dnah5hlb612/Dnah5hlb612	involves: C57BL/6J	J:130755	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Dock1

Allelic Composition	Genetic Background	Reference	Phenotypes
Dock1b2b3190Clo/Dock1b2b3190Clo	C57BL/6J-Dock1^b2b3190Clo	J:175213	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Fgf8

Allelic Composition	Genetic Background	Reference	Phenotypes
Fgf8tm1.3Mrt/Fgf8tm1.4Mrt Tg(Msx2-cre)5Rem/0	involves: 129P2/OlaHsd	J:66266	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Hey2

Allelic Composition	Genetic Background	Reference	Phenotypes
Hey2tm1Uts/Hey2tm1Uts	either: (involves: 129X1/SvJ) or (involves: C57BL/6)	J:79025	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Invs

Allelic Composition	Genetic Background	Reference	Phenotypes
Invsinv/Invsinv	FVB/N-Invs^inv	J:48533	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Mks1

Allelic Composition	Genetic Background	Reference	Phenotypes
Mks1avc6/Mks1avc6	involves: C57BL/6J * FVB/N	J:163196	View
Del(11Mpo-Chad)18Brd/+	involves: 129S7/SvEvBrd * C57BL/6	J:109163	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Ntf3

Allelic Composition	Genetic Background	Reference	Phenotypes
Ntf3tm1Par/Ntf3tm1Par	involves: 129S1/Sv	J:35639	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Gene: Phc1

Allelic Composition	Genetic Background	Reference	Phenotypes
Phc1tm1Os/Phc1tm1Os	involves: 129S2/SvPas * C57BL/6	J:43764	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot

Allelic Composition	Genetic Background	Reference	Phenotypes
Dp(16Lipi-Zbtb21)1Yey/0	involves: 129S7/SvEvBrd	J:121790	View

Mouse Models

Human Disease Modeled: tetralogy of Fallot
Associated Mouse Cytogenetic Marker: Del(11Mpo-Chad)18Brd

Allelic Composition	Genetic Background	Reference	Phenotypes
Del(11Mpo-Chad)18Brd/+	involves: 129S7/SvEvBrd * C57BL/6	J:109163	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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