X-Linked immunodeficiency 74 (DOID:0112063)
Alliance: disease page
Synonyms: IMD74; respiratory insufficiency due to SARS-CoV-2 viral infection; TLR7 deficiency; X-linked immunodeficiency 74,COVID-19-related
Alt IDs: OMIM:301051
Definition: A T cell deficiency characterized by severe respiratory insufficiency in response to infection with the COVID19 coronavirus and impaired signaling through the TLR7 pathway that has_material_basis_in hemizygous mutation in the TLR7 gene on chromosome Xp22.2.