immunodeficiency with hyper-IgM type 4 (DOID:0060760)
Alliance: disease page
Synonyms: HIGM4; hyper-IgM syndrome type 4
Alt IDs: OMIM:608184, MESH:C564277, NCI:C564277, ORDO:101091, UMLS_CUI:C1842413
Definition: A hyper IgM syndrome that is characterized by normal or increased serum IgM concentrations associated with low or absent serum IgG, IgA, and IgE concentrations, indicating a defect in the class-switch recombination (CSR) process.