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Human Disease and Mouse Model Detail
Human Disease Amyotrophic Lateral Sclerosis 10, with or without Frontotemporal Dementia;
OMIM ID: 612069
Synonyms Amyotrophic Lateral Sclerosis
View all models View ALL (7) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Gene is associated with the disease in this species
      Mouse Homologs Human Homologs Mouse Models Mouse : Human
Homology Class
     Tardbp TARDBP*   1:1 Homology
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(CAG-dsRed2/RNAi:Tardbp)6Zxu View 1 model
  Tg(Prnp-TARDBP)3cPtrc View 1 model
  Tg(Prnp-TARDBP)4Jlel View 1 model
  Tg(Prnp-TARDBP*A315T)23Jlel View 1 model
  Tg(Prnp-TARDBP*A315T)95Balo View 1 model
References Disease References using Mouse Models (7)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory