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Human Disease and Mouse Model Detail
Human Disease Myelofibrosis
OMIM ID: 254450
View all models View ALL (7) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Human Homologs Mouse Homologs Mouse Models Homology Source
     JAK2* Jak2* View 3 models HomoloGene
     GATA1 Gata1* View 2 models HomoloGene and HGNC
MYB Myb* View 1 model HomoloGene
NCOR2 Ncor2* View 1 model HomoloGene and HGNC
     CALR* Calr   HomoloGene and HGNC
MPL* Mpl   HomoloGene and HGNC
SH2B3* Sh2b3   HomoloGene and HGNC
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(H2-Kb-Jak2*V617F)2Shmd View 1 model
  Tg(Vav1-JAK2*V617F)AZjz View 1 model
References Disease References using Mouse Models (9)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory