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Human Disease and Mouse Model Detail
Human Disease Myelofibrosis
OMIM ID: 254450
View all models View ALL (7) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Mouse Homologs Human Homologs Mouse Models Mouse : Human
Homology Class
     Jak2* JAK2* View 3 models 1:1 Homology
     Gata1* GATA1 View 2 models 1:1 Homology
Myb* MYB View 1 model 1:1 Homology
Ncor2* NCOR2 View 1 model 1:1 Homology
     Calr CALR*   1:1 Homology
Mpl MPL*   1:1 Homology
Sh2b3 SH2B3*   1:1 Homology
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(H2-Kb-Jak2*V617F)2Shmd View 1 model
  Tg(Vav1-JAK2*V617F)AZjz View 1 model
References Disease References using Mouse Models (9)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory