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Disease Ontology Browser
pulmonary hemosiderosis (DOID:12118)
Synonyms: brown induration; brown lung; Idiopathic pulmonary hemosiderosis
Alt IDs: OMIM:178550, OMIM:235500, DOID:0050330, ICD10CM:J84.03, ICD9CM:516.1, MESH:C536281, ORDO:99931, UMLS_CUI:C0020807
Definition: A lung disease with an unknown etiology affecting the lungs which results in bleeding from tiny alveolar capillaries. Examination of sputum and bronchoalveolar lavage fluid can disclose hemosiderin-laden alveolar macrophages (siderophages), and the lung biopsy shows numerous siderophages in the alveoli. Alveolar hemorrhage is characterized by hemoptysis, dyspnea, alveolar infiltrates on chest radiograph, and various degrees of anaemia. Following a bleeding episode, the alveolar macrophages convert the hemoglobin's iron into hemosiderin within 36-72h.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory