| Human Disease |
Systemic Lupus Erythematosus; SLE OMIM ID: 152700 |
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| View all models | View ALL (47) mouse models for this human disease. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Genes and mouse models |
Mutations in human and/or mouse homologs are associated with this disease
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Transgenes and other genome features |
Transgenes and other genome features developed in mice to model this disease.
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| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Dnase1tm1Tmo/Dnase1tm1Tmo |
involves: 129P2/OlaHsd * C57BL/6 | J:62549 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Fcgr2btm1Ttk/Fcgr2btm1Ttk |
B6.129S4-Fcgr2btm1Ttk | J:64152 | View |
| Fcgr2btm1Ttk/Fcgr2btm1Ttk Traf3ip2tm1Sbn/Traf3ip2+ |
involves: 129 * 129S4/SvJae * C57BL/6 | J:191090 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| C1qatm1Mjw/C1qatm1Mjw |
involves: 129P2/Ola * 129S/SvEv * C57BL/6 | J:47315 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Cdkn1atm1Led/Cdkn1atm1Led |
involves: 129S6/SvEvTac | J:76041 | View |
| Cdkn1atm1Led/Cdkn1atm1Led Gadd45atm1Ajf/Gadd45atm1Ajf |
either: (involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6) | J:76041 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Def6Gt(OST307148)Lex/Def6Gt(OST307148)Lex |
involves: 129S5/SvEvBrd * C57BL/6 | J:106469 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Cd19tm1(cre)Cgn/Cd19+ Ep300tm2Reck/Ep300+ |
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 | J:147840 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Ccr2tm1Blck/Ccr2tm1Blck Faslpr/Faslpr |
MRL.Cg-Ccr2tm1Blck Faslpr | J:113343 | View |
| Faslpr/Faslpr Tnfrsf9tm1Byk/Tnfrsf9tm1Byk |
MRL.Cg-Tnfrsf9tm1Byk Faslpr | J:120559 | View |
| Faslpr/Faslpr Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+ |
MRL.Cg-Faslpr Igh-Jtm2(3H9-VDJ*)Mwg | J:131138 | View |
| Faslpr/Faslpr Tlr9tm1Aki/Tlr9tm1Aki |
MRL.Cg-Tlr9tm1Aki Faslpr | J:113557 | View |
| Faslpr/Faslpr |
MRL/Mp-Faslpr | J:27634, J:28885, J:108760, J:131138 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Gadd45atm1Ajf/Gadd45atm1Ajf |
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129X1/SvJ * C57BL/6) | J:76041 | View |
| Cdkn1atm1Led/Cdkn1atm1Led Gadd45atm1Ajf/Gadd45atm1Ajf |
either: (involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6) | J:76041 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Ikzf3tm1Kge/Ikzf3tm1Kge |
involves: 129S4/SvJae * C57BL/6 | J:50626, J:81805 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Junbtm3Wag/Junbtm3Wag Tg(KRT5-cre)1Tak/0 |
involves: 129/Sv * 129P2/OlaHsd * C3H * C57BL/6 | J:155575 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Lyntm1Ard/Lyntm1Ard |
involves: 129P2/OlaHsd | J:161523 | View |
| KitW-sh/KitW-sh Lyntm1Ard/Lyntm1Ard |
involves: 101 * 129P2/OlaHsd * C3H/HeH | J:161523 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Man2a1tm1Jxm/Man2a1tm1Jxm |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:74579 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Mta2tm1.1Yzha/Mta2tm1.1Yzha |
involves: 129S4/SvJae * C57BL/6 * FVB/N | J:137101 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Ppargtm1.1Gonz/Ppargtm1.1Gonz Lyz2tm1(cre)Ifo/Lyz2+ |
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 | J:168799 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Ptprctm1Weis/Ptprctm1Weis |
involves: 129X1/SvJ * C57BL/6 | J:66501 | View |
| Ptprctm1Weis/Ptprc+ |
involves: 129X1/SvJ * C57BL/6 | J:66501 | View |
| Ptpn22tm2Achn/Ptpn22tm2Achn Ptprctm1Weis/Ptprctm1Weis |
B6.Cg-Ptprctm1Weis Ptpn22tm2Achn | J:147129 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Rasgrp1lag/Rasgrp1lag |
involves: 129 * C57BL/6 | J:85189 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Rassf5tm1Kina/Rassf5tm1Kina |
B6.Cg-Rassf5tm1Kina | J:168749 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Rc3h1san/Rc3h1san |
either: C57BL/6-Rc3h1san or (involves: C57BL/6 * CBA/Ca) | J:98938 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Rxratm1Krc/Rxratm1Krc Lyz2tm1(cre)Ifo/Lyz2+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 | J:168799 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tnfrsf13btm1Vmd/Tnfrsf13btm1Vmd |
involves: C57BL/6 | J:82331 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix |
B6.129-Traf3ip2tm1.1Lix | J:187766 | View |
| Fcgr2btm1Ttk/Fcgr2btm1Ttk Traf3ip2tm1Sbn/Traf3ip2+ |
involves: 129 * 129S4/SvJae * C57BL/6 | J:191090 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Trove2tm1Woln/Trove2tm1Woln |
B6.129S1-Trove2tm1Woln | J:84627 | View |
| Trove2tm1Woln/Trove2tm1Woln |
involves: 129S1/Sv * C57BL/6 | J:84627 | View |
| Trove2tm1Woln/Trove2+ |
involves: 129S1/Sv * C57BL/6 | J:84627 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Ptpn22tm2Achn/Ptpn22tm2Achn Ptprctm1Weis/Ptprctm1Weis |
B6.Cg-Ptprctm1Weis Ptpn22tm2Achn | J:147129 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+ |
B6.129P2-Igh-Jtm2(3H9-VDJ*)Mwg | J:142389 | View |
| Cd4tm1Mak/Cd4tm1Mak Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+ |
B6.Cg-Cd4tm1Mak Igh-Jtm2(3H9-VDJ*)Mwg | J:142389 | View |
| Faslpr/Faslpr Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+ |
MRL.Cg-Faslpr Igh-Jtm2(3H9-VDJ*)Mwg | J:131138 | View |
| Tcrbtm1Mom/Tcrbtm1Mom Tcrdtm1Mom/Tcrdtm1Mom Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+ |
B6.129P2-Tcrbtm1Mom Igh-Jtm2(3H9-VDJ*)Mwg Tcrdtm1Mom | J:142389 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(ACTB-TNFRSF6B)754Jwu/? |
B6.Cg-Tg(Actb-TNFRSF6B)754Jwu | J:148162 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Igh-V-CD40lg)#Tsub/0 |
C57BL/6-Tg(Igh-V-CD40lg)#Tsub | J:128824 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| X/Yaa |
(NZB x BXSB)F1 | J:6235 | View |
| X/Yaa |
(NZW x BXSB)F1 | J:7276 | View |
| X/Yaa |
(NZW x SB)F1 | J:7276 | View |
| X/Yaa |
BXSB/MpJ | J:6235, J:108760, J:7308 | View |
| X/Yaa |
BXSB/MpJScr | J:10973 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Csf2tm1Dran/Csf2tm1Dran Il3tm1Glli/Il3tm1Glli |
B6.129S2-Csf2tm1Dran Il3tm1Glli | J:83086 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Psen1tm1Bdes/Psen1+ Psen2tm1Bdes/Psen2tm1Bdes |
involves: 129P2/OlaHsd | J:91235 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Ightm1(Igh564)Tik/Ightm1(Igh564)Tik Igktm1(Igk564)Tik/Igktm1(Igk564)Tik |
B6.129S4-Igktm1(Igk564)Tik Ightm1(Igh564)Tik | J:113555 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Csf2tm1Dran/Csf2tm1Dran Ifngtm1Ts/Ifngtm1Ts Il3tm1Glli/Il3tm1Glli |
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 | J:83086 | View |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/22/2013 MGI 5.13 |
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