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Human Disease and Mouse Model Detail
Human Disease Systemic Lupus Erythematosus; SLE
OMIM ID: 152700
Synonyms Systemic Lupus Erythematosus
View all models View ALL (52) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Gene is associated with the disease in this species
      Mouse Homologs Human Homologs Mouse Models Mouse : Human
Homology Class
     C4b*, C4a C4A*, C4B View 1 model 2:2 Homology
Dnase1* DNASE1* View 1 model 1:1 Homology
Fcgr2b* FCGR2B* View 2 models 1:1 Homology
     C1qa* C1QA View 1 model 1:1 Homology
Cdkn1a* CDKN1A View 2 models 1:1 Homology
Def6* DEF6 View 1 model 1:1 Homology
Ep300* EP300 View 1 model 1:1 Homology
Fas* FAS View 5 models 1:1 Homology
Gadd45a* GADD45A View 2 models 1:1 Homology
Ikzf3* IKZF3 View 1 model 1:1 Homology
Jak1* JAK1 View 1 model 1:1 Homology
Junb* JUNB View 1 model 1:1 Homology
Lyn* LYN View 2 models 1:1 Homology
Man2a1* MAN2A1 View 1 model 1:1 Homology
Mta2* MTA2 View 1 model 1:1 Homology
Polb* POLB View 1 model 1:1 Homology
Pparg* PPARG View 1 model 1:1 Homology
Prdm1* PRDM1 View 1 model 1:1 Homology
Ptprc* PTPRC View 3 models 1:1 Homology
Rasgrp1* RASGRP1 View 1 model 1:1 Homology
Rassf5* RASSF5 View 1 model 1:1 Homology
Rc3h1* RC3H1 View 1 model 1:1 Homology
Rxra* RXRA View 1 model 1:1 Homology
Tnfrsf13b* TNFRSF13B View 1 model 1:1 Homology
Traf3ip2* TRAF3IP2 View 2 models 1:1 Homology
Trove2* TROVE2 View 3 models 1:1 Homology
     Bank1 BANK1*   1:1 Homology
Ptpn22 PTPN22* View 1 model 1:1 Homology
Trex1 TREX1*   1:1 Homology
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Igh-J View 4 models
  Tg(ACTB-TNFRSF6B)754Jwu View 1 model
  Tg(Igh-V-CD40lg)#Tsub View 1 model
  Tg(Tlr7)1Boll View 1 model
  Yaa View 5 models
References Disease References using Mouse Models (55)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory