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Human Disease and Mouse Model Detail
Human Disease Diabetes Mellitus, Noninsulin-Dependent; NIDDM
OMIM ID: 125853
Synonyms Diabetes Mellitus, Noninsulin-Dependent; Diabetes Mellitus, Type II; T2D; Noninsulin-Dependent Diabetes Mellitus
View all models View ALL (43) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Human Homologs Mouse Homologs Mouse Models Homology Source
     AKT2* Akt2* View 1 model HomoloGene and HGNC
CDKAL1* Cdkal1* View 1 model HomoloGene and HGNC
GCK* Gck* View 2 models HomoloGene
HMGA1* Hmga1* View 2 models HGNC
HNF1A* Hnf1a* View 1 model HomoloGene
IRS1* Irs1* View 3 models HomoloGene and HGNC
IRS2* Irs2* View 4 models HomoloGene and HGNC
SLC2A2* Slc2a2* View 1 model HomoloGene and HGNC
     ASIP a* View 1 model HomoloGene and HGNC
AR Ar* View 1 model HomoloGene and HGNC
CTF1 Ctf1* View 1 model HomoloGene and HGNC
CYB5R4 Cyb5r4* View 1 model HomoloGene and HGNC
FEM1B Fem1b* View 1 model HomoloGene
FOXM1 Foxm1* View 1 model HomoloGene
GADD45GIP1 Gadd45gip1* View 1 model HomoloGene and HGNC
HTR2C Htr2c* View 1 model HomoloGene and HGNC
INS Ins2* View 1 model HomoloGene
LEP Lep* View 1 model HomoloGene and HGNC
LEPR Lepr* View 7 models HomoloGene and HGNC
MAFA Mafa* View 1 model HomoloGene and HGNC
PHOX2A Phox2a* View 2 models HomoloGene and HGNC
PPP1R3A Ppp1r3a* View 1 model HomoloGene and HGNC
PPP1R3C Ppp1r3c* View 1 model HomoloGene and HGNC
PRKCI Prkci* View 1 model HomoloGene and HGNC
SLC2A4 Slc2a4* View 1 model HomoloGene
     ABCC8* Abcc8   HomoloGene and HGNC
ENPP1* Enpp1   HomoloGene and HGNC
GCGR* Gcgr   HomoloGene
GPD2* Gpd2   HomoloGene
HNF1B* Hnf1b   HomoloGene
HNF4A* Hnf4a   HomoloGene and HGNC
IGF2BP2* Igf2bp2   HomoloGene and HGNC
KCNJ11* Kcnj11   HomoloGene and HGNC
LIPC* Lipc   HomoloGene
MAPK8IP1* Mapk8ip1   HomoloGene
MTNR1B* Mtnr1b   HomoloGene
NEUROD1* Neurod1   HomoloGene and HGNC
PAX4* Pax4   HomoloGene
PDX1* Pdx1 View 1 model HomoloGene and HGNC
PPARG* Pparg   HomoloGene
PTPN1* Ptpn1   HomoloGene
RETN* Retn   HomoloGene and HGNC
SLC30A8* Slc30a8   HomoloGene and HGNC
TCF7L2* Tcf7l2   HomoloGene and HGNC
WFS1* Wfs1   HomoloGene and HGNC
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(aP2-SREBF1c)9884Reh View 1 model
  Tg(Ckm-IGF1R*K1003R)1Dlr View 1 model
  Tg(UcpDta)1Kz View 2 models
  Timo View 1 model
References Disease References using Mouse Models (86)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory