Human Disease	Amyotrophic Lateral Sclerosis 1; ALS1 OMIM ID: 105400
Synonyms	Amyotrophic Lateral Sclerosis 1, Familial; FALS
View all models	View ALL (45) mouse models for this human disease.
Genes and mouse models	Mutations in human and/or mouse homologs are associated with this disease       *Gene is associated with the disease in this species       Mouse Homologs Human Homologs Mouse Models Mouse : Human Homology Class        Sod2* SOD2 View 1 model 1:1 Homology Vegfa* VEGFA View 1 model 1:1 Homology        Dctn1 DCTN1*   1:1 Homology Nefh NEFH*   1:1 Homology Prph PRPH*   1:1 Homology Sod1 SOD1*   1:1 Homology
Transgenes and other genome features	Transgenes and other genome features developed in mice to model this disease.      Transgenes and Other Genome Features Mouse Models   Tg(NEFH)200Jpj View 2 models   Tg(NFH)120Jpj View 2 models   Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo View 1 model   Tg(SOD1*)125Dbo View 1 model   Tg(SOD1*)DF7Yaw View 2 models   Tg(SOD1*G37R)1Dwc View 2 models   Tg(SOD1*G37R)9Dpr View 1 model   Tg(SOD1*G37R)29Dpr View 1 model   Tg(SOD1*G37R)42Dpr View 1 model   Tg(SOD1*G37R)106Dpr View 1 model   Tg(SOD1*G85R)74Dwc View 1 model   Tg(SOD1*G85R)148Dwc View 1 model   Tg(SOD1*G85R)#Roos View 2 models   Tg(Sod1*G86R)M1Jwg View 1 model   Tg(SOD1*G93A)1Gur View 5 models   Tg(SOD1*G93A)2Gur View 1 model   Tg(SOD1*G93A)dl1Gur View 2 models   Tg(SOD1*G127X)716Mrkl View 1 model   Tg(SOD1*H46R)#Maw View 1 model   Tg(SOD1*H46R*H48Q)58Dbo View 1 model   Tg(SOD1*H46R*H48Q)139Dbo View 1 model   Tg(SOD1*L126Z)#Deng View 2 models   Tg(TARDBP)#Jpj View 1 model   Tg(TARDBP*A315T)#Jpj View 1 model   Tg(TARDBP*G348C)#Jpj View 1 model   Tg(Thy1-Sncg)HvP36Putt View 1 model   Tg(Thy1-SOD1*G93A)T3Hgrd View 2 models   Tg(Thy1-TARDBP)4Singh View 2 models   Tg(Thy1-TARDBP)6Singh View 1 model