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Gene Expression Data
Assay Details
Assay
Reference: J:28941 Igarashi P, et al., Cloning, embryonic expression, and alternative splicing of a murine kidney-specific Na-K-Cl cotransporter. Am J Physiol. 1995 Sep;269(3 Pt 2):F405-18
Assay type: RNA in situ
MGI Accession ID: MGI:6357745
Gene symbol: Slc12a1
Gene name: solute carrier family 12, member 1
Probe: isoform B
Probe preparation: Antisense RNA labelled with P33
Visualized with: Autoradiography
Assay notes: Represents isoform B.
Results
Specimen 3D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: renal cortex Strong 3D Most highly expressed.
TS28: outer renal medulla Present 3D Minor hybridization signal, probably reflected cross-hybridization with the much more abundant F isoform.

Specimen 4A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical renal tubule Present Regionally restricted 4A Expressed in a subpopulation of tubules that were in direct contact with the vascular poles of glomeruli, as well as tubules that extended from the outer medulla toward glomeruli.
TS28: glomerular tuft Absent 4A
TS28: renal proximal convoluted tubule Absent 4A

Specimen 4B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical renal tubule Present Regionally restricted 4B Expressed in a subpopulation of tubules that were in direct contact with the vascular poles of glomeruli, as well as tubules that extended from the outer medulla toward glomeruli.
TS28: glomerular tuft Absent 4B
TS28: renal proximal convoluted tubule Absent 4B

Specimen 7 top: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: nephrogenic zone Strong Regionally restricted 7_top Expressed in tubules that were in direct contact with maturing glomeruli but was absent from the subcapsular nephrogenic zone.
TS24: renal tubule Strong Regionally restricted 7_top Expressed in tubules that were in direct contact with maturing glomeruli but was absent from the subcapsular nephrogenic zone.
TS24: ureteric tip Absent 7_top ureteric bud
TS24: cap mesenchyme Absent 7_top
TS24: comma-shaped body Absent 7_top
TS24: s-shaped body Absent 7_top

Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: renal cortex Present
TS24: renal medulla Present
TS24: collecting duct Absent
TS24: renal vesicle Absent
TS24: immature loop of Henle Strong


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory