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Gene Expression Data
Assay Details
Assay
Reference: J:74069 Morris-Wiman J, et al., Temporospatial distribution of matrix metalloproteinase and tissue inhibitors of matrix metalloproteinases during murine secondary palate morphogenesis. Anat Embryol (Berl). 2000 Aug;202(2):129-41
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6342622
Gene symbol: Mmp3
Gene name: matrix metallopeptidase 3
Antibody: anti-Mmp-3
Detection system: fluorescein
Assay notes: Fixation with acid alcohol.
Results
Specimen 2G: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: palatal shelf mesenchyme Present Widespread 2G Expression in all regions of mesenchyme. Relative expression greater within nasal area.
TS20: dental placode Present Regionally restricted 2G Expression within palatal basement membrane of medial and oral epithelium, and tooth germ.
TS20: oral epithelium Present Regionally restricted 2G Expression within palatal basement membrane of medial and oral epithelium, and tooth germ.

Specimen 2H: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Strong Regionally restricted 2H Expression increased in all regions of palatal mesenchyme, enhanced in nasomedial and central regions. except tooth germ and adjacent lateral mesenchyme.
TS21: palatal shelf epithelium Present Regionally restricted 2H Expression in all regions of palatal epithelial basement membrane. Increased expression within nasal and oral basement membrane.

Specimen 2I: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Strong Regionally restricted 2I Intense expression within all regions of palatal mesenchyme. Increased expression within dorsal medial nasal, maxillary and central mesenchymal regions, including mesenchyme surrounding regressing palatal seam. Expression in ventral medial and mid-oral mesenchyme less profound than in adjacent mesenchymal regions.
TS22: palatal shelf epithelium Present Regionally restricted 2I Expression in all regions of palatal epithelial basement membrane, associated with nasal palatal epithelium, and within cells of the palatal seam.

Specimen gd 14-fused not shown: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present Uniform Expression almost uniformly distributed throughout palatal mesenchyme, with only slight increases in expression associated with mesenchymal bridge and forming bone.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory