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Gene Expression Data
Assay Details
Assay
Reference: J:125184 Yamamoto M, et al., Cloning and characterization of a novel MyoD enhancer-binding factor. Mech Dev. 2007 Sep-Oct;124(9-10):715-28
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5578632
Gene symbol: Zfp704
Gene name: zinc finger protein 704
Reporter: lacZ
Direct Detection
Results
Specimen 5A: embryonic day 9.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS15: mesonephros mesenchyme Strong 5A
TS15: branchial arch Present 5A
TS15: otocyst Present 5A
TS15: somite Present Regionally restricted 5A Expression is in the anterior somites.
TS15: trunk mesenchyme Present Regionally restricted 5A Expression is in the flank mesenchyme just posterior to the emerging forelimb buds.
TS15: notochord Weak 5A

Specimen 5B: embryonic day 10.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS17: mesonephros mesenchyme Strong 5B
TS17: branchial arch Present 5B
TS17: forelimb bud apical ectodermal ridge Present 5B
TS17: hindlimb bud apical ectodermal ridge Present 5B
TS17: otocyst Present 5B
TS17: somite Present Regionally restricted 5B Expression is in the anterior somites extending to the hindlimb level and is strongest in the epaxial domain.
TS17: trunk mesenchyme Present Regionally restricted 5B Expression is in the flank mesenchyme just posterior to the emerging forelimb buds.
TS17: forelimb bud mesenchyme Present Regionally restricted 5B Expression is in the centro-medial limb bud mesenchyme.
TS17: notochord Present Regionally restricted 5B Expression is in the posterior region.

Specimen 5C: embryonic day 11.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present 5C
TS19: limb Present Regionally restricted 5C Expression is in proximal regions.
TS19: myotome Present Regionally restricted 5C Expression is strongest in the epaxial domain, weak in a portion of the hypaxial myotome.
TS19: notochord Present Regionally restricted 5C Expression is in the posterior region.

Specimen 5E: embryonic day 11.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS19: neural tube Present Regionally restricted 5E Expression is ventral.
TS19: neural tube basal columns Present 5E
TS19: neural tube floor plate Present 5E
TS19: neural tube roof plate Present 5E

Specimen 5F: embryonic day 11.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS19: 1st branchial groove epithelium Present 5F
TS19: thyroid gland Present 5F
TS19: branchial arch Present Regionally restricted 5F Expression is in branchial arch-derived muscle precursors.
TS19: blood vessel Present Regionally restricted 5F Expression is in cells of the vascular wall.
TS19: 2nd branchial arch ectoderm Present Regionally restricted 5F Expression is in the ectoderm between arches 2 and 3.
TS19: 3rd branchial arch ectoderm Present Regionally restricted 5F Expression is in the ectoderm between arches 2 and 3.

Specimen 5G: embryonic day 11.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS19: dorsal aorta Present 5G
TS19: sympathetic ganglion Present 5G

Specimen 5H: embryonic day 11.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS19: endolymphatic appendage Present 5H
TS19: inner ear epithelium Present 5H

Specimen 5I: embryonic day 11.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS19: notochord Present Regionally restricted 5I Expression is in the posterior region.
TS19: surface ectoderm Present 5I

Specimen 8A: embryonic day 11.5; Zfp704tm1Glh/Zfp704+ (more )
Note: Double labeled: blue - Zfp704 reporter; purple/brown - Scx (assay MGI:5578630).
Structure Level Pattern Image Note
TS19: limb mesenchyme Present 8A
TS19: somite Present 8A
TS19: rib pre-cartilage condensation Absent 8A

Specimen 8B: embryonic day 12.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS20: hindlimb Present 8B Expression is in the centro-medial portion of the limb bud.

Specimen 8D: embryonic day 14.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS22: forelimb Strong Regionally restricted 8D Expression is in the distal tendon elements.
TS22: forelimb digit skin Strong 8D
TS22: hand Strong 8D
TS22: forelimb digit Strong Regionally restricted 8D Expression is in the joints.

Specimen 8E: embryonic day 14.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS22: forelimb digit 2 Very strong Regionally restricted 8E Expression is in the ventral tendons, less strong in the dorsal tendon.
TS22: forelimb digit 3 Very strong Regionally restricted 8E Expression is in the ventral tendons, less strong in the dorsal tendon.
TS22: forelimb digit 4 Very strong Regionally restricted 8E Expression is in the ventral tendons, less strong in the dorsal tendon.

Specimen 8E inset: embryonic day 14.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS22: forelimb digit 3 Present Regionally restricted 8E inset Expression is in the joints.

Specimen 8F: embryonic day 14.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS22: forelimb digit Present Regionally restricted 8F Expression is in the ventral and dorsal tendons and developing musculature.
TS22: forelimb digit mesenchyme Present
TS22: forelimb digit skin Present

Specimen 8G: embryonic day 14.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS22: forearm Present Regionally restricted 8G Expression is in some but not all of the tendon rudiments.

Specimen 8H: embryonic day 14.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS22: upper arm Present Regionally restricted 8H Expression is in muscle, absent in tendons.

Specimen Table 1: embryonic day 11.5; Zfp704tm1Glh/Zfp704+ (more )
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present
TS19: cervical sinus Present
TS19: endocardial cushion Present
TS19: endolymphatic appendage Present
TS19: inner ear Present
TS19: metanephric mesenchyme Present
TS19: myotome Present
TS19: neural retinal epithelium Present
TS19: neural tube basal columns Present
TS19: neural tube floor plate Present
TS19: neural tube roof plate Present
TS19: surface ectoderm Present
TS19: sympathetic ganglion Present
TS19: thyroid gland Present
TS19: head Present Regionally restricted Expression is in muscle precursors.
TS19: limb Present Regionally restricted Expression is in tendons and muscle precursors.
TS19: trunk mesenchyme Present Regionally restricted Expression is in flank mesenchyme just posterior to forelimb buds.
TS19: blood vessel Present Regionally restricted Expression is in the vascular wall.
TS19: heart Present Regionally restricted Expression is in the truncus arteriosus cushion mesenchyme.
TS19: intestine epithelium Present Regionally restricted
TS19: notochord Present Regionally restricted Expression is in the posterior region.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory