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Gene Expression Data
Assay Details
Assay
Reference: J:171052 Itou J, et al., HMGB factors are required for posterior digit development through integrating signaling pathway activities. Dev Dyn. 2011 May;240(5):1151-62
Assay type: RNA in situ
MGI Accession ID: MGI:5298595
Gene symbol: Shh
Gene name: sonic hedgehog
Results
Specimen 3A: embryonic day 10.0 (more )
Note: 28 somite stage.
Structure Level Pattern Image Note
TS16: forelimb bud Present 3A

Specimen 3B: embryonic day 10.0; Hmgb1tm1Meb/Hmgb1tm1Meb, Hmgb2tm1Meb/Hmgb2+ (more )
Note: 28 somite stage.
Structure Level Pattern Image Note
TS16: forelimb bud Absent 3B

Specimen 3E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 3E Expression was detected in the posterior mesenchyme.

Specimen 3F: embryonic day 10.5; Hmgb1tm1Meb/Hmgb1tm1Meb, Hmgb2tm1Meb/Hmgb2+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 3F Expression was detected in the posterior mesenchyme, but it was lower than in the control limb bud.

Specimen 4A: embryonic day 10.5 (more )
Note: Also stained for Fgf8 (assay MGI:5298600).
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 4A Expression was detected in the posterior mesenchyme.

Specimen 4B: embryonic day 10.5 (more )
Note: Also stained for Fgf8 (assay MGI:5298600).
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 4B Expression was detected in the posterior mesenchyme.

Specimen 4C: embryonic day 10.5; Hmgb1tm1Meb/Hmgb1tm1Meb, Hmgb2tm1Meb/Hmgb2+ (more )
Note: Also stained for Fgf8 (assay MGI:5298600).
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 4C Expression was lower in the posterior mesenchyme compared to the control limb bud.

Specimen 4D: embryonic day 10.5; Hmgb1tm1Meb/Hmgb1tm1Meb, Hmgb2tm1Meb/Hmgb2+ (more )
Note: Also stained for Fgf8 (assay MGI:5298600).
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 4D Expression was lower in the posterior mesenchyme compared to the control limb bud.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory