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Gene Expression Data
Assay Details
Assay
Reference: J:161427 Jones B, et al., The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure. PLoS Genet. 2008;4(9):e1000190
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:4462039
Gene symbol: Dot1l
Gene name: DOT1-like, histone H3 methyltransferase (S. cerevisiae)
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 7.5; Dot1ltm1Tche/Dot1l+ (more )
Structure Level Pattern Image Note
TS11: embryo Present Ubiquitous 2A

Specimen 2B: embryonic day 9.5; Dot1ltm1Tche/Dot1l+ (more )
Structure Level Pattern Image Note
TS15: embryo Present Ubiquitous 2B
TS15: 1st branchial arch Strong Ubiquitous 2B
TS15: central nervous system Strong Ubiquitous 2B
TS15: heart Strong Ubiquitous 2B
TS15: optic vesicle Strong Ubiquitous 2B
TS15: otic pit Strong Ubiquitous 2B

Specimen 2C: embryonic day 9.5; Dot1ltm1Tche/Dot1l+ (more )
Structure Level Pattern Image Note
TS15: yolk sac endoderm Present 2C
TS15: yolk sac mesenchyme Present 2C
TS15: blood Present 2C Expression is in primitive erythrocytes.

Specimen Not shown E10.5: embryonic day 10.5; Dot1ltm1Tche/Dot1l+ (more )
Structure Level Pattern Image Note
TS17: embryo Present Ubiquitous

Specimen Not shown E11.5: embryonic day 11.5; Dot1ltm1Tche/Dot1l+ (more )
Structure Level Pattern Image Note
TS19: embryo Present Ubiquitous

Specimen Not shown E12.5: embryonic day 12.5; Dot1ltm1Tche/Dot1l+ (more )
Structure Level Pattern Image Note
TS20: embryo Present Ubiquitous


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory