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Gene Expression Data
Assay Details
Assay
Reference: J:117061 Goebbels S, et al., Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice. Genesis. 2006 Dec;44(12):611-21
Assay type: Recombinase reporter
MGI Accession ID: MGI:4429157
Gene symbol: Neurod6
Gene name: neurogenic differentiation 6
Reporter: lacZ
Direct Detection
Results
Specimen Fig. 2d: embryonic day 13.5; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: telencephalon Strong Regionally restricted 2d Staining is observed in the dorsal telencephalon, and absent from the ventricular zone and entire basal telencephalon.
TS21: cortical plate Strong Regionally restricted 2d Staining is observed prominently in the cortical plate of the dorsal telencephalon.
TS21: cerebral cortex ventricular layer Absent 2d
Specimen Fig. 2e: embryonic day 13.5; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: hindbrain Present Regionally restricted 2e Staining is observed in the medullary reticular formation, cochlear nuclei, and differentiation fields of the deep cerebellar nuclei.
Specimen Fig. 2f: embryonic day 13.5; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: medulla oblongata Present Regionally restricted 2f Staining is observed in the dorsal horn outside of the ventricular zone.
Specimen Fig. 3a: postnatal adult; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: hippocampus Present 3a
TS28: dentate gyrus Present 3a
TS28: subiculum Present 3a
Specimen Fig. 3d: postnatal adult; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cortical layer II Strong 3d
TS28: cortical layer III Strong 3d
TS28: cortical layer IV Strong 3d
TS28: cortical layer V Strong 3d
TS28: cortical layer VI Strong 3d
TS28: hippocampus Strong 3d
TS28: anterior olfactory nucleus Strong 3d Staining is observed in the dorsal and ventral anterior olfactory nuclei.
TS28: deep cerebellar nucleus Present 3d
TS28: gigantocellular reticular nucleus Present 3d
TS28: pontine nucleus Present 3d
TS28: supramammillary nucleus Present 3d
TS28: vestibular nucleus Present 3d
Specimen Fig. 3e: postnatal adult; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Present Regionally restricted 3e Staining is observed in the dorsal horn of the spinal cord.
Specimen Fig. 4a top pane: postnatal adult; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: dentate gyrus Present Regionally restricted 4a top
TS28: hippocampus CA3 Present 4a top
Specimen Fig. 4a middle pane: postnatal adult; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present 4a middle Staining is observed in granule cells in the outer shell.
Specimen Fig. 5a A: postnatal day 20; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: neocortex Present Regionally restricted 5aA Staining is observed in projection neurons, but not in oligodendrocytes.
TS28: hippocampus CA1 Present Regionally restricted 5aA Staining is observed in projection neurons, but not in oligodendrocytes.
Specimen Fig. 5a B: postnatal day 20; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: telencephalon Present Regionally restricted 5aB Staining is observed in projection neurons, but not in oligodendrocytes.
Specimen Fig. 5a C: postnatal day 20; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: neocortex Present Regionally restricted 5aC Staining is observed in projection neurons, but not in oligodendrocytes.
TS28: hippocampus CA1 Present Regionally restricted 5aC Staining is observed in projection neurons, but not in oligodendrocytes.
Specimen Fig. 5a D: postnatal day 20; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: telencephalon Present Regionally restricted 5aD Staining is observed in projection neurons, but not in oligodendrocytes.
Specimen Fig. 5a E: postnatal day 20; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present Regionally restricted 5aE Staining is observed in projection neurons, but not in oligodendrocytes.
Specimen Fig. 5a F: postnatal day 13; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: telencephalon Present Regionally restricted 5aF Staining is observed in projection neurons, but not in astrocytes.
Specimen Fig. 6c: postnatal adult; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted 6c Staining is observed in projection neurons, but not in interneurons.
TS28: neocortex Present Regionally restricted 6c Staining is observed in projection neurons, but not in interneurons.
Specimen Fig. 6d: postnatal adult; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted 6d Staining is observed in projection neurons, but not in interneurons.
TS28: neocortex Present Regionally restricted 6d Staining is observed in projection neurons, but not in interneurons.
Specimen Fig. 6e: postnatal adult; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted 6e Staining is observed in projection neurons, but not in interneurons.
TS28: neocortex Present Regionally restricted 6e Staining is observed in projection neurons, but not in interneurons.
Specimen Fig. 6f: postnatal adult; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted 6f Staining is observed in projection neurons, but not in interneurons.
TS28: neocortex Present Regionally restricted 6f Staining is observed in projection neurons, but not in interneurons.
Specimen Supplemental Figure: postnatal month 1; Neurod6tm1(cre)Kan/Neurod6+, Tg(CAG-cat,-lacZ)1Brn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: brain Strong Supplemental
TS28: spinal cord Strong Supplemental
TS28: heart Absent Supplemental
TS28: liver Absent Supplemental
TS28: lung Absent Supplemental
TS28: metanephros Absent Supplemental
TS28: musculature Absent Supplemental
TS28: pancreas Absent Supplemental
TS28: peripheral nerve Absent Supplemental
TS28: spleen Absent Supplemental
TS28: thymus Weak Supplemental Weak staining is observed in the thymus.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/09/2024
MGI 6.23 		The Jackson Laboratory