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Gene Expression Data
Assay Details
Assay
Reference: J:144373 Kinameri E, et al., Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. PLoS One. 2008;3(12):e3859
Assay type: RNA in situ
MGI Accession ID: MGI:3852046
Gene symbol: Prdm12
Gene name: PR domain containing 12
Results
Specimen 2B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: cranial preganglion Present 2B
TS15: future spinal cord Present 2B
TS15: future forebrain Weak Regionally restricted 2B Expression was detected in the caudal forebrain.
TS15: future midbrain Weak 2B

Specimen 2E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: cranial ganglion Present 2E
TS17: dorsal root ganglion Present 2E
TS17: future spinal cord Present 2E
TS17: forebrain Present Regionally restricted 2E Expression in the caudal forebrain was stronger at E10.5 than at E9.5.
TS17: midbrain Present 2E Expression in the midbrain was stronger at E10.5 than at E9.5.

Specimen 2G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 2G Expression was detected in several regions in the diencephalon, p3, p1, and hypothalamus.
TS17: midbrain Present Regionally restricted 2G Expression was detected in a small dorsal region in the midbrain.
TS17: hindbrain Present Regionally restricted 2G Expression was detected in the ventral hindbrain.

Specimen 2H: embryonic day 10.5 (more )
Note: Double labeled: blue - Prdm12; brown - Shh (assay MGI:3852054).
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 2H Expression was detected in postmitotic neurons adjacent to, but not overlapping the zona limitans intrathalamica.

Specimen 2I, 2J, 2K: embryonic day 10.5 (more )
Note: Fig. 2J and 2K are boxed regions in Fig. 2I that are shown at higher magnification. Double labeled: blue - Prdm12; brown - Shh (assay MGI:3852054).
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 2J , 2I Expression was detected in postmitotic neurons adjacent to, but not overlapping the zona limitans intrathalamica.
TS17: diencephalon lateral wall ventricular layer Present Regionally restricted 2I , 2K Expression was detected in the p1 region in the diencephalic ventricular zone but was excluded from the dorsal midline.

Specimen 3D: embryonic day 11.5 (more )
Note: Double labeled: blue - Prdm12; brown - Dbx1 (assay MGI:3852058).
Structure Level Pattern Image Note
TS19: neural tube ventricular layer Present Regionally restricted 3D Expression was detected in progenitor domain p1.
TS19: dorsal root ganglion Strong 3D

Specimen 3E: embryonic day 11.5 (more )
Note: Double labeled: blue - Prdm12; brown - Olig2 (assay MGI:3852136).
Structure Level Pattern Image Note
TS19: neural tube ventricular layer Present Regionally restricted 3E Expression was detected in progenitor domain p1.
TS19: dorsal root ganglion Strong 3E

Specimen 3M: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube mantle layer Present Regionally restricted 3M Expression was detected in both proliferating cells in the ventricular zone and adjacent postmitotic neurons in the mantle zone.
TS19: neural tube ventricular layer Present Regionally restricted 3M Expression was detected in both proliferating cells in the ventricular zone and adjacent postmitotic neurons in the mantle zone.

Specimen 4B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon ventricular layer Present Graded 4B Expression was detected in the dorsal telencephalic ventricular zone with a steep lateral/strong to medial/weak gradient from the pallium and subpallium boundary.
TS20: telencephalon Present Regionally restricted 4B Expression was detected in the septum.
TS20: corpus striatum Present 4B

Specimen 4G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon ventricular layer Present Graded 4G Expression was detected in the dorsal telencephalic ventricular zone with a steep lateral/strong to medial/weak gradient from the pallium and subpallium boundary.
TS20: diencephalon Present Regionally restricted 4G Expression was detected in the lateral region of the prethalamus.

Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Absent
TS24: telencephalon Present Regionally restricted Expression was detected in the septum.

Specimen 5H: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: dorsomedial hypothalamic nucleus Present 5H

Specimen 5I: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: zona incerta Present Regionally restricted 5I Expression was detected in the dorsal half of the zona incerta of the thalamus.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory