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Gene Expression Data
Assay Details
Assay
Reference: J:135081 Schmidt H, et al., The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord. J Cell Biol. 2007 Oct 22;179(2):331-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3828046
Gene symbol: Ntrk1
Gene name: neurotrophic tyrosine kinase, receptor, type 1
Antibody: anti-TrkA
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 3E Wt Thoracic: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: spinal cord lateral wall Present Regionally restricted 3E Thoracic WT Expression is in the dorsal funiculus.

Specimen 3E Wt Lumbar: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: spinal cord lateral wall Present Regionally restricted 3E Lumbar WT Expression is in the dorsal funiculus.

Specimen 3E cn/cn Thoracic: embryonic day 13.0; Npr2cn/Npr2cn (more )
Structure Level Pattern Image Note
TS21: spinal cord lateral wall Present Regionally restricted 3E Thoracic cn/cn Expression in the dorsal funiculus in this mutant is 64.1% of the wild-type controls at thoracic levels.

Specimen 3E cn/cn Lumbar: embryonic day 13.0; Npr2cn/Npr2cn (more )
Structure Level Pattern Image Note
TS21: spinal cord lateral wall Present Regionally restricted 3E Lumbar cn/cn Expression in the dorsal funiculus in this mutant is 59% of the wild-type controls at the lumbar trunk levels.

Specimen 3F: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: spinal cord lateral wall Present Regionally restricted 3F Expression is in the dorsal funiculus.

Specimen 3G: embryonic day 13.0; Npr2cn/Npr2cn (more )
Structure Level Pattern Image Note
TS21: spinal cord lateral wall Present Regionally restricted 3G Expression is in the dorsal funiculus and in a small group of axons penetrating into the dorsal horn growing further in the direction of the central canal.

Specimen 4A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: spinal cord Present 4A

Specimen 4B: embryonic day 15.0; Npr2cn/Npr2cn (more )
Structure Level Pattern Image Note
TS23: spinal cord Present 4B Expression is the same as in wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory