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Gene Expression Data
Assay Details
Assay
Reference: J:116886 Yoon D, et al., Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development. J Biol Chem. 2006 Sep 1;281(35):25703-11
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3710965
Gene symbol: Tfrc
Gene name: transferrin receptor
Antibody: anti-transferrin receptor
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 5B TfR +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: yolk sac endoderm Present Regionally restricted 5B TfR +/+ Expression was detected in visceral endoderm.
TS15: extraembryonic vascular system Weak Regionally restricted 5B TfR +/+ Expression was detected in endothelial cells.
TS15: yolk sac mesenchyme Weak 5B TfR +/+
Specimen 5B TfR -/-: embryonic day 9.5; Hif1atm1Jhu/Hif1atm1Jhu (more )
Structure Level Pattern Image Note
TS15: yolk sac endoderm Weak Regionally restricted 5B TfR -/- Expression was markedly decreased in visceral endoderm in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory