About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:92862 Grohmann K, et al., Characterization of Ighmbp2 in motor neurons and implications for the pathomechanism in a mouse model of human spinal muscular atrophy with respiratory distress type 1 (SMARD1). Hum Mol Genet. 2004 Sep 15;13(18):2031-42
Assay type: Western blot
MGI Accession ID: MGI:3055359
Gene symbol: Ighmbp2
Gene name: immunoglobulin mu binding protein 2
Antibody: anti-Ighmpb2
Detection system: Secondary antibody coupled to horseradish peroxidase
Results Image: 1B
 Sample Information Bands Other Sample Information
Lane AgeStructure 110 kDa (b) 55 kDa Genetic BackgroundMutant Allele(s)Sex
wt brain E15.0 (a) TS23: brain Present (c) Present involves: C57BL/6 * C57BLKS/J Not Specified
mut brain E15.0 (a) TS23: brain Not Specified Present B6.BKS-Ighmbp2nmd-2J/J Ighmbp2nmd-2J/Ighmbp2nmd-2JNot Specified
wt spinal cord E15.0 (a) TS23: spinal cord Present (c) Present involves: C57BL/6 * C57BLKS/J Not Specified
mut spinal cord E15.0 (a) TS23: spinal cord Not Specified Present B6.BKS-Ighmbp2nmd-2J/J Ighmbp2nmd-2J/Ighmbp2nmd-2JNot Specified
wt muscle E15.0 (a) TS23: skeletal muscle Present (c) Present involves: C57BL/6 * C57BLKS/J Not Specified
mut muscle E15.0 (a) TS23: skeletal muscle Not Specified Present B6.BKS-Ighmbp2nmd-2J/J Ighmbp2nmd-2J/Ighmbp2nmd-2JNot Specified
wt heart E15.0 (a) TS23: heart Weak Present involves: C57BL/6 * C57BLKS/J Not Specified
mut heart E15.0 (a) TS23: heart Not Specified Present B6.BKS-Ighmbp2nmd-2J/J Ighmbp2nmd-2J/Ighmbp2nmd-2JNot Specified
wt lung E15.0 (a) TS23: lung Present Present involves: C57BL/6 * C57BLKS/J Not Specified
mut lung E15.0 (a) TS23: lung Not Specified Present B6.BKS-Ighmbp2nmd-2J/J Ighmbp2nmd-2J/Ighmbp2nmd-2JNot Specified
wt liver E15.0 (a) TS23: liver Weak Present involves: C57BL/6 * C57BLKS/J Not Specified
mut liver E15.0 (a) TS23: liver Not Specified Present B6.BKS-Ighmbp2nmd-2J/J Ighmbp2nmd-2J/Ighmbp2nmd-2JNot Specified
HEK 293 + HA-Ighmbp2 Control
brain/pre-absorption control Control
brain/pre-immune control Control
Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) This band represents the full length protein. Authors stated that expression levels were strongly reduced in the mutants.
(c) This was one of the tissues with the highest expression level.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/14/2020
MGI 6.14
The Jackson Laboratory