Gene Expression Data
Assay Details
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Assay
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Reference:
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J:54095
Inada M, et al., Maturational disturbance of chondrocytes in Cbfa1-deficient mice. Dev Dyn. 1999 Apr;214(4):279-90
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3043267
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Gene symbol:
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Pthlh
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Gene name:
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parathyroid hormone-like peptide
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Probe:
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PTHrP cDNA1
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
8 +/+ tibia PTHrP:
embryonic day 18.5
(more  )
Specimen
8 +/+ tibia PTHrP:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: tibia |
Present |
Regionally restricted |
8+/+ tibia PTHrP
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Expression was detected in osteoblasts in bone marrow and in bone collar but was weak in chondrocytes, except for terminal hypertrophic chondrocytes.
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Specimen
8 -/- tibia PTHrP:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: tibia |
Weak |
Regionally restricted |
8-/- tibia PTHrP
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Expression was weak in chondrocytes but was absent from the perichondrial region.
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Specimen
8 -/- femur PTHrP:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: femur |
Weak |
Regionally restricted |
8-/- femur PTHrP
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Expression was weak in chondrocytes but was absent from the perichondrial region.
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Analysis Tools