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Gene Expression Data
Assay Details
Assay
Reference: J:73071 Long F, et al., Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development. 2001 Dec;128(24):5099-108
Assay type: RNA in situ
MGI Accession ID: MGI:2178838
Gene symbol: Ihh
Gene name: Indian hedgehog
Probe: Ihh probe2
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 5 Ihh E14.5 WT: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tibia cartilage condensation Present 5_Ihh WT E14.5 Expression was present in prehypertrophic chondrocytes.

Specimen 5 Ihh E14.5 Cre10;Smon/c: embryonic day 14.5; Smotm1Amc/Smotm2Amc, Tg(Col2a1-cre)10Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: tibia cartilage condensation Present Regionally restricted 5_Ihh Cre10;Smon/c E14.5 Expression was present in prehypertrophic chondrocytes similar to wild type.

Specimen 5 Ihh E14.5 Ihhn/n: embryonic day 14.5; Ihhtm1Amc/Ihhtm1Amc (more )
Structure Level Pattern Image Note
TS22: tibia cartilage condensation Absent 5_Ihh Ihhn/n E14.5

Specimen 5 Ihh E18.5 WT: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: tibia Present 5_Ihh WT E18.5

Specimen 5 Ihh E18.5 Cre10;Smon/c: embryonic day 18.5; Smotm1Amc/Smotm2Amc, Tg(Col2a1-cre)10Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: tibia Present Regionally restricted 5_Ihh Cre10;Smon/c E18.5 Expression was maintained along the longitudinal axis of the tibia similar to the wild type.

Specimen 5 Ihh E18.5 Ihhn/n: embryonic day 18.5; Ihhtm1Amc/Ihhtm1Amc (more )
Structure Level Pattern Image Note
TS26: tibia Absent 5_Ihh Ihhn/n E18.5

Specimen 7B mIhh WT: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: tibia Present 7B mIhh WT E16.5


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory