Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Leprdb-Pas
Name:	leptin receptor; diabetes Institut Pasteur
MGI ID:	MGI:1856013
Synonyms:	dbPas, diabetes-Pasteur, obese-like
Gene:	Lepr  Location: Chr4:101574601-101672549 bp, + strand  Genetic Position: Chr4, 46.96 cM
Alliance:	Leprdb-Pas page

Strain of Origin:

DW/Pas

Allele Type:    Spontaneous Mutation:    Duplication   Leprdb-Pas involves 1 genes/genome features (Lepr) View all   Mutation details: Southern analysis indicates that the mutation in the Pas allele is a partial duplication of the coding sequence for the putative extracellular domain of the protein. (J:31419, J:49607) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lepr Mutation:	121 strains or lines available

Original:	J:31095 Guenet JL, A mutation in the DW inbred line producting an obese phenotype. Mouse News Lett. 1982;67:30
All:	7 reference(s)