Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Foxd3tm2Lby
Name:	forkhead box D3; targeted mutation 2, Patricia A Labosky
MGI ID:	MGI:2388721
Synonyms:	Foxd3-, Foxd3Gfp
Gene:	Foxd3  Location: Chr4:99544536-99546859 bp, + strand  Genetic Position: Chr4, 45.71 cM
Alliance:	Foxd3tm2Lby page

Germline Transmission:	Earliest citation of germline transmission: J:79491
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region of the endogenous gene was replaced with a cassette containing GFP. A fusion transcript consisting of the endogenous 5' untranslated region and GFP was produced. GFP fluorescence was detected in the neural crest after 8.5 dpc. (J:79491)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	21 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxd3 Mutation:	10 strains or lines available

Original:	J:79491 Hanna LA, et al., Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo. Genes Dev. 2002 Oct 15;16(20):2650-61
All:	10 reference(s)