Tcf7tm1.1Abh
Targeted Allele Detail
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Symbol: |
Tcf7tm1.1Abh |
Name: |
transcription factor 7, T cell specific; targeted mutation 1.1, Avinash Bhandoola |
MGI ID: |
MGI:6718433 |
Synonyms: |
Tcf7YFP |
Gene: |
Tcf7 Location: Chr11:52143198-52174158 bp, - strand Genetic Position: Chr11, 31.86 cM
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Alliance: |
Tcf7tm1.1Abh page
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Germline Transmission: |
Earliest citation of germline transmission:
J:306903
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Parent Cell Line: |
EAP6 (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Reporter) |
Mutation: |
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Insertion
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Mutation details: Sequence for the ribosome-skipping P2A was inserted before the stop codon in exon 10, followed by YFP reporter gene sequence. The loxP site flanked neomycin resistance gene cassette that was inserted into intron 9 was removed through subsequent cre-mediated recombination.
(J:306903)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tcf7 Mutation: |
24 strains or lines available
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Original: |
J:306903 Harly C, et al., The transcription factor TCF-1 enforces commitment to the innate lymphoid cell lineage. Nat Immunol. 2019 Sep;20(9):1150-1160 |
All: |
3 reference(s) |
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