Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Tcf7tm1.1Abh
Name:	transcription factor 7, T cell specific; targeted mutation 1.1, Avinash Bhandoola
MGI ID:	MGI:6718433
Synonyms:	Tcf7YFP
Gene:	Tcf7  Location: Chr11:52143198-52174158 bp, - strand  Genetic Position: Chr11, 31.86 cM
Alliance:	Tcf7tm1.1Abh page

Germline Transmission:	Earliest citation of germline transmission: J:306903
Parent Cell Line:	EAP6 (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: Sequence for the ribosome-skipping P2A was inserted before the stop codon in exon 10, followed by YFP reporter gene sequence. The loxP site flanked neomycin resistance gene cassette that was inserted into intron 9 was removed through subsequent cre-mediated recombination. (J:306903)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcf7 Mutation:	24 strains or lines available

Original:	J:306903 Harly C, et al., The transcription factor TCF-1 enforces commitment to the innate lymphoid cell lineage. Nat Immunol. 2019 Sep;20(9):1150-1160
All:	3 reference(s)