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Nr4a3tm1.1Mono
Targeted Allele Detail
Summary
Symbol: Nr4a3tm1.1Mono
Name: nuclear receptor subfamily 4, group A, member 3; targeted mutation 1.1, Masahiro Ono
MGI ID: MGI:6507444
Synonyms: Nr4a3-Tocky
Gene: Nr4a3  Location: Chr4:48045153-48086447 bp, + strand  Genetic Position: Chr4, 26.07 cM, cytoband B2
Alliance: Nr4a3tm1.1Mono page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:264610
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsUsing BAC RP23-122N18, the first coding exon was replaced with a cassette containing the Fast Fluorescent Timer gene, poly(A) signal sequences and a loxP site flanked neomycin resistance gene cassette. The neo cassette was removed through subsequent cre-mediated recombination. The FT gene is a mutated form of mCherry (M18V E34K K69R L84W S149T A224S). (J:264610)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr4a3 Mutation:  53 strains or lines available
References
Original:  J:264610 Bending D, et al., A timer for analyzing temporally dynamic changes in transcription during differentiation in vivo. J Cell Biol. 2018 Aug 6;217(8):2931-2950
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory