Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Lhx6tm3.1Vpa
Name:	LIM homeobox protein 6; targeted mutation 3.1, Vassilis Pachnis
MGI ID:	MGI:6466660
Synonyms:	Lhx6Fl
Gene:	Lhx6  Location: Chr2:35971965-35995420 bp, - strand  Genetic Position: Chr2, 24.17 cM
Alliance:	Lhx6tm3.1Vpa page

Germline Transmission:	Earliest citation of germline transmission: J:268552
Parent Cell Line:	E14TG2a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: LoxP sites were inserted in non-coding regions just 5 to coding exon 1b, and 3 to coding exon 3. An frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. (J:268552)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lhx6 Mutation:	27 strains or lines available

Original:	J:268552 Denaxa M, et al., Modulation of Apoptosis Controls Inhibitory Interneuron Number in the Cortex. Cell Rep. 2018 Feb 13;22(7):1710-1721
All:	4 reference(s)