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Fmo3tm1.2Jmbn
Targeted Allele Detail
Summary
Symbol: Fmo3tm1.2Jmbn
Name: flavin containing monooxygenase 3; targeted mutation 1.2, J Mark Brown
MGI ID: MGI:6458899
Gene: Fmo3  Location: Chr1:162781369-162812097 bp, - strand  Genetic Position: Chr1, 70.34 cM
Alliance: Fmo3tm1.2Jmbn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:279143
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn FRT-flanked lacZ reporter and selection cassette with a 3 loxP site was inserted upstream of exon 5. An additional loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the reporter/selection cassette. Cre-mediated recombination removed exon 5. (J:279143)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fmo3 Mutation:  40 strains or lines available
References
Original:  J:279143 Shih DM, et al., Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report. Arterioscler Thromb Vasc Biol. 2019 Jun;39(6):1045-1054
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory