Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fmo3em1Jmbn
Name:	flavin containing monooxygenase 3; endonuclease-mediated mutation 1, J Mark Brown
MGI ID:	MGI:6458889
Gene:	Fmo3  Location: Chr1:162781369-162812097 bp, - strand  Genetic Position: Chr1, 70.34 cM
Alliance:	Fmo3em1Jmbn page

Strain of Origin:

C57BL/6

Allele Type:    Endonuclease-mediated (Null/knockout) Mutation:    Intragenic deletion   Mutation details: CRISPR-targeting of exon 2 produced a 7 bp deletion with a premature termination at amino acid position 98. (J:254352, J:279143)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fmo3 Mutation:	40 strains or lines available

Original:	J:254352 Schugar RC, et al., The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue. Cell Rep. 2017 Jun 20;19(12):2451-2461
All:	2 reference(s)