Fli1tm1.1Anmb
Targeted Allele Detail
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| Symbol: |
Fli1tm1.1Anmb |
| Name: |
Friend leukemia integration 1; targeted mutation 1.1, Andreea M Bujor |
| MGI ID: |
MGI:6454699 |
| Synonyms: |
Fli1flox |
| Gene: |
Fli1 Location: Chr9:32333500-32454157 bp, - strand Genetic Position: Chr9, 17.74 cM
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| Alliance: |
Fli1tm1.1Anmb page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:294088
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129
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| Allele Type: |
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Targeted (Conditional ready) |
| Mutation: |
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Insertion
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Mutation details: KOMP knockout-first clone HTGR06010_A_1_C02 (comprising FRT site, En2 splice acceptor, IRES, LacZ gene, poly(A) signal sequence, loxP site, neomycin resistance gene cassette, loxP site in intron 2, exon 3, and loxP site in intron 3) was used to create a conditional-ready allele through the removal of the lacZ and neo cassettes via flp-mediated recombination. Exon 3 was floxed.
(J:294088)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Fli1 Mutation: |
26 strains or lines available
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| Original: |
J:294088 Bujor AM, et al., Fli1 Downregulation in Scleroderma Myeloid Cells Has Profibrotic and Proinflammatory Effects. Front Immunol. 2020;11:800 |
| All: |
1 reference(s) |
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Analysis Tools
