Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Prps1em1H
Name:	phosphoribosyl pyrophosphate synthetase 1; endonuclease-mediated mutation 1, Harwell
MGI ID:	MGI:6451735
Synonyms:	PRPS1-R214W-EM1-B6
Gene:	Prps1  Location: ChrX:139357362-139376889 bp, + strand  Genetic Position: ChrX, 61.35 cM, cytoband F1-F2
Alliance:	Prps1em1H page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Not Specified) Mutation:    Single point mutation   Mutation details: CRISPR-targeting introduced the amino acid substitution of arginine with tryptophan at position 214 (R214W). (J:90559)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prps1 Mutation:	19 strains or lines available

Original:	J:90559 The Mammalian Genetics Unit at Harwell, Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK. Unpublished. 2004-2013;
All:	1 reference(s)