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Runx2em1(IMPC)Rbrc
Endonuclease-mediated Allele Detail
Summary
Symbol: Runx2em1(IMPC)Rbrc
Name: runt related transcription factor 2; endonuclease-mediated mutation 1, RIKEN BioResource Center
MGI ID: MGI:6402897
Gene: Runx2  Location: Chr17:44806873-45125518 bp, - strand  Genetic Position: Chr17, 21.33 cM
Alliance: Runx2em1(IMPC)Rbrc page
IMPC: Runx2 gene page
Mutation
origin
Strain of Origin:  C57BL/6NJcl
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele from IMPC was generated at RIKEN BioResource Research Center by injecting CAS9 Protein and 2 guide sequences AGAACTCGCTCCTAATTTCATGG, AATCGCCAGTGTATTTGAAGTGG, which resulted in a Exon Deletion. (J:265051)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Runx2 Mutation:  42 strains or lines available
References
Original:  J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory