Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Phpt1tm1Eys
Name:	phosphohistidine phosphatase 1; targeted mutation 1, Edward Y Skolnik
MGI ID:	MGI:6401822
Gene:	Phpt1  Location: Chr2:25463442-25465236 bp, - strand  Genetic Position: Chr2, 17.44 cM, cytoband A3
Alliance:	Phpt1tm1Eys page

Germline Transmission:	Earliest citation of germline transmission: J:262099
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	B6(Cg)-Tyrc-2J/J

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A loxP site, neomycin resistance gene cassette, beta-galactoside gene cassette and a second loxP site were inserted into intron 1. A third loxP site was inserted into intron 3. (J:262099)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Phpt1 Mutation:	12 strains or lines available

Original:	J:262099 Srivastava S, et al., Regulation of KATP Channel Trafficking in Pancreatic beta-Cells by Protein Histidine Phosphorylation. Diabetes. 2018 May;67(5):849-860
All:	1 reference(s)