Summary | Mutation origin | Mutation description | Tumor data | Find Mice (IMSR) | References

Symbol:	Ascl1tm2.1Fgu
Name:	achaete-scute family bHLH transcription factor 1; targeted mutation 2.1, Francois Guillemot
MGI ID:	MGI:6388406
Gene:	Ascl1  Location: Chr10:87326681-87329522 bp, - strand  Genetic Position: Chr10, 43.64 cM
Alliance:	Ascl1tm2.1Fgu page

Germline Transmission:	Earliest citation of germline transmission: J:217912
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of the coding sequence. A Venus gene with a 5' loxP site and an FRT-flanked neo cassette were inserted downstream of the 3' UTR. Flp-mediated recombination removed the selection cassette. (J:174732, J:217912)

List all tumor models in MMHCdb carrying Ascl1tm2.1Fgu

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ascl1 Mutation:	28 strains or lines available

Original:	J:217912 Andersen J, et al., A transcriptional mechanism integrating inputs from extracellular signals to activate hippocampal stem cells. Neuron. 2014 Sep 3;83(5):1085-97
All:	2 reference(s)