Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Il4tm1Wep
Name:	interleukin 4; targeted mutation 1, William E Paul
MGI ID:	MGI:2388163
Gene:	Il4  Location: Chr11:53503287-53509492 bp, - strand  Genetic Position: Chr11, 31.97 cM
Alliance:	Il4tm1Wep page

Germline Transmission:	Earliest citation of germline transmission: J:67964
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Disruption caused by insertion of vector   Mutation details: Exon 1 and 178 nucleotides of intron 1 were replaced with an enhanced GFP floxed-neo construct via homologous recombination. Heterozygous mutant animals were identified by PCR genotype analysis. (J:67964)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il4 Mutation:	42 strains or lines available

Original:	J:67964 Hu-Li J, et al., Regulation of expression of IL-4 alleles: analysis using a chimeric GFP/IL-4 gene. Immunity. 2001 Jan;14(1):1-11
All:	2 reference(s)