Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Smarcd3tm1.2Bbr
Name:	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3; targeted mutation 1.2, Benoit G Bruneau
MGI ID:	MGI:6368007
Synonyms:	Baf60c-
Gene:	Smarcd3  Location: Chr5:24797620-24829649 bp, - strand  Genetic Position: Chr5, 11.93 cM, cytoband A3
Alliance:	Smarcd3tm1.2Bbr page

Germline Transmission:	Earliest citation of germline transmission: J:257963
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 1-4 were flanked by loxP sites and a FRT-flanked neomycin resistance gene was inserted upstream of exon 1. Flp-mediated recombination removed the selection cassette and cre-mediated recombination deleted exons 1-4. (J:257963)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smarcd3 Mutation:	25 strains or lines available

Original:	J:257963 Sun X, et al., Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function. Biol Open. 2018 Jan 5;7(1):bio029512
All:	1 reference(s)