Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Rxfp2tm1Aia
Name:	relaxin/insulin-like family peptide receptor 2; targeted mutation 1, Alexander I Agoulnik
MGI ID:	MGI:2388129
Synonyms:	Greatko
Gene:	Rxfp2  Location: Chr5:149942140-150005649 bp, + strand  Genetic Position: Chr5, 89.23 cM
Alliance:	Rxfp2tm1Aia page

Germline Transmission:	Earliest citation of germline transmission: J:79124
Parent Cell Line:	AB2.1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutations:    Duplication, Insertion   Rxfp2tm1Aia involves 1 genes/genome features (Rxfp2) View all   Mutation details: Gene targeting resulted in the duplication of exons 12-16 and the insertion of vector sequence into the 16 intron of the endogenous gene. (J:79124)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rxfp2 Mutation:	53 strains or lines available

Original:	J:79124 Gorlov IP, et al., Mutations of the GREAT gene cause cryptorchidism. Hum Mol Genet. 2002 Sep 15;11(19):2309-18
All:	12 reference(s)